Results 101 to 110 of about 39,888 (323)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Эндодонтия TodayINTRODUCTION. Soft tissue plastic surgery is usually accompanied by the harvesting of a gingival graft from the hard palate. The exposed donor wound surface may cause pain and the possibility of wound infection cannot be ruled out. Medical adhesives have
Yu. A. Bakaev +6 more
doaj +1 more source
Environment‐Dependent Adhesive Behaviors of Mussel‐Inspired Coordinate‐Crosslinked Bioadhesives
Macromolecular Materials and Engineering, 2020 Mussel‐inspired, coordinate‐crosslinked gels have attracted extensive attention but their adhesive behaviors are still not fully understood. Herein, four mussel‐inspired molecules with different molecular characteristics are synthesized to study their ...
Sidi Li +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
The importance of incorporating technological advancements into the artificial eye process: a perspective commentary [PDF]
, 2017 Application of technology into healthcare has typically been targeted to high demand illnesses and treatments. However, with an increasing need to meet patient’s expectations combined with increased accessibility and reduced costs, smaller healthcare ...
Chinnery, H. +4 more
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Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Re-evaluating Student Treatments of Barkcloth Artefacts from the Economic Botany Collection, Royal Botanic Gardens, Kew [PDF]
, 2017 Since 1995 textile conservation students have treated 17 pieces of barkcloth from the Economic Botany Collection, Royal Botanic Gardens, Kew. A re-examination of 8 treated objects has enabled comparison of the effectiveness of interventive treatments ...
Lennard, Frances +2 more
core
An animal experimental study on pubourethral ligament restoration with platelet rich plasma for the treatment of stress urinary incontinence. [PDF]
, 2019 Introduction: Minimally invasive methods for injured ligament and tendon restoration have been developed and gained popularity in recent years. Injury and relaxation of the pubourethral ligament (PUL) can lead to stress urinary incontinence (SUI).
Chrysanthopoulou, E +6 more
core +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source