Results 81 to 90 of about 15,688 (284)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Emerging bone adhesives for early fixation and enhanced healing of fractures

Materials & Design
Fractures are prevalent in clinical orthopedics. Conventional metal implants used for fracture fixation pose risks of iatrogenic injury and infection, and often fail to achieve precise alignment in complex cases.
Wenbo Li, Shouye Sun, Yuhang Tian, Wen Yin, Baoming Yuan, Dankai Wu, Chuangang Peng   +6 more
doaj   +1 more source

Avaliação da integração de enxerto de pele com a utilização do 2-octilcianoacrilato: estudo experimental em ratos Evaluation of skin graft integration using 2-octil-cyanocrylate: experimental study in rats

Acta Cirúrgica Brasileira, 2000
A fixação dos enxertos de pele total através da sutura demanda tempo cirúrgico relativamente longo. O surgimento de adesivos teciduais tem se apresentado com várias aplicações clínicas, constituindo alternativa à sutura convencional.
Gilvani Azor de Oliveira e Cruz, Renato Silva Freitas, José Fillus Neto, André Ricardo Dall'Oglio Tolazzi, Anne Karoline Groth, Maria de Lourdes Pessole Biondo-Simões   +5 more
doaj   +1 more source

Mussel-inspired hydrogel tissue adhesives for wound closure

, 2017
Tissue adhesives have been introduced as a promising alternative for the traditional wound closure method of suturing.
Wen Zhong, Maedeh Rahimnejad
core   +1 more source

Temperature-sensitive mussel-inspired citrate-based tissue adhesives with low-swelling

, 2022
Mussel-inspired tissue adhesives have been widely studied in recent years because of their excellent underwater adhesion. Our recent study has synthesized a series of tissue adhesives with citric acid, dopamine, 1,8-octanediol and poly(ethylene oxide ...
Jinghong Ma (1755838), Yiwen Xu (747278), Yali Ji (2553436)   +2 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

The Usefulness of Leukosan SkinLink for Simple Facial Laceration Repair in the Emergency Department

Archives of Plastic Surgery, 2015
Background Repair of facial laceration in the emergency department can pose a number of difficulties. Children can be uncooperative, but adults can also be if they have sustained head trauma or are intoxicated.
Hyunjoo Kim, Junhyung Kim, Jaehoon Choi, Woonhyuk Jung   +3 more
doaj   +1 more source

Cyanoacrylate tissue adhesives - effective securement technique for intravascular catheters: in vitro testing of safety and feasibility

, 2012
Partial or complete dislodgement of intravascular catheters remains a significant problem in hospitals despite current securement methods. Cyanoacrylate tissue adhesives (TA) are currently used to close skin wounds as an alternative to sutures.
Smyth, D J, Simonova, G, Dunster, K., K. R. Dunster, Simonova, G., G. Simonova, Smyth, Danielle, Fraser, J.F., Dunster, K, Fraser, J., Dunster, K.R., Rickard, C.M., Rickard, C M, McMillan, David, McMillan, D., C. M. Rickard, Dunster, Kimble, Smyth, D., McMillan, D J, D. McMillan, D. J. Smyth, Fraser, J F, J. F. Fraser, Smyth, D.J., Simonova, Gabriela, Rickard, Claire, Fraser, John   +26 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Phacoemulsification Incision-Creation, Evaluation and Closure: A Review

Delhi Journal of Ophthalmology, 2019
Creating an ideal incision is the foremost and the most crucial step in phacoemulsification. The most commonly used incision for phacoemulsification is sutureless clear corneal incision (CCI).
Ajay Kumar Singh
doaj   +1 more source