Results 61 to 70 of about 4,737,680 (328)

From Adhesion to Detachment: Strategies to Design Tissue‐Adhesive Hydrogels

open access: yesAdvanced NanoBiomed Research
The use of tissue adhesives dates to 1940s when surgical glues were introduced for wound closure applications. However, current clinically used tissue adhesives (fibrin and cyanoacrylate glues) have limited adhesion strength and biocompatibility issues ...
Minh Hieu Ho   +7 more
doaj   +1 more source

An evaluation of properties related to wear time of four dressings during a five-day period [PDF]

open access: yes, 2015
This study evaluated skin tolerance and other properties relating to wear time, such as conformability and comfort, pain on dressing removal, adhesion and premature detachment, of four advanced hydrated dressings applied to the knees and elbows of 22 ...
Bielfeldt, Stephen   +2 more
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A Mechanically Resilient and Tissue‐Conformable Hydrogel with Hemostatic and Antibacterial Capabilities for Wound Care

open access: yesAdvanced Science, 2023
Hydrogels are used in wound dressings because of their tissue‐like softness and biocompatibility. However, the clinical translation of hydrogels remains challenging because of their long‐term stability, water swellability, and poor tissue adhesiveness ...
Jae Park   +10 more
doaj   +1 more source

Tissue adhesives in otorhinolaryngology

open access: yesLaryngo- rhino- otologie, 2009
GMS Current Topics in Otorhinolaryngology - Head and Neck Surgery; 8:Doc01; ISSN 1865 ...
openaire   +4 more sources

Providing adhesion for a miniture mobile intra-abdominal device based on biomimetic principles [PDF]

open access: yes, 2009
This paper investigates the surface adhesion characteristics required for a miniature mobile device to move around the abdominal cavity. Such a device must be capable of adhering to the tissue lining and move freely across the upper surface of the ...
Gaskell, P.H.   +5 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

In vitro evaluation of tissue adhesives composed of hydrophobically modified gelatins and disuccinimidyl tartrate

open access: yesScience and Technology of Advanced Materials, 2012
The effect of the hydrophobic group content in gelatin on the bonding strength of novel tissue–penetrating tissue adhesives was evaluated. The hydrophobic groups introduced into gelatin were the saturated hexanoyl, palmitoyl, and stearoyl groups, and the
Miyuki Matsuda, Tetsushi Taguchi
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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