Results 61 to 70 of about 15,688 (284)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Hydrogel Adhesives for Gastrointestinal Perforation: Design Principles and Applications

Exploration
Gastrointestinal (GI) perforation, as an acute digestive condition, is difficult to heal spontaneously and requires prompt surgical intervention or bioactive adhesives to promote wound closure.
Yudi Pang, Shuai Tian, Qinyu Han, Yulin Deng, Jiatao Zhang, Enqiang Linghu, Qianqian Chen, Zhimin Wang   +7 more
doaj   +1 more source

Research Progress and Design Strategy of Hemostatic Adhesives

Zhongguo yiliao qixie zazhi
Adhesives have emerged as an effective method for wound closure, hemostasis and tissue engineering in recent years, which not only are suitable for the adhesion of wet tissues, but also can adapt to the peristalsis and mechanical stretching of tissues ...
Chenyu ZHAO, Han WANG, Qianqian HAN
doaj   +1 more source

Avaliação de sistemas adesivos universais na dentina sob testes de microtração e espectroscopia micro-raman [PDF]

, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Odontologia, Florianópolis, 2014.Avaliar o efeito da aplicação de cargas mecânicas cíclicas sobre a resistência adesiva à microtração de ...
Farias, David Cardoso Sandes
core  

Adhesives : tissue repair and reconstruction

, 2017
In recent years, new modalities of tissue repair have emerged replacing traditional wound closure techniques such as suturing. Biocompatible adhesives are at the forefront of this “surgical revolution” as fi brin, polyethylene glycol and cyanoacrylate ...
Ruprai, Herleen (R18642), H. Ruprai, A. Lauto, J.M. Hook, Lauto, Antonio (R12400), Hook, James   +5 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

TRANSSPHENOIDAL SURGERY OF NASAL LIQUORRHEA AS A COMPLICATION AFTER TREATMENT OF PROLACTINOMAS WITH DRUGS

Вестник хирургии имени И.И. Грекова, 2018
The objective of the research is to optimize the method of transnasal endoscopic plasty of liquor fistulas in patients with prolactinomas, who got nasal liquorrhea against the background of treatment with dopamine agonists.Material and methods ...
A. V. Polezhaev, V. Yu. Cherebillo, D. V. Svistov, U. A. Tsoy, D. V. Voitsekhovsky   +4 more
doaj   +1 more source

Antibacterial and biodegradable tissue nano-adhesives for rapid wound closure

, 2018
Meng-meng Lu,1,2 Jing Bai,3 Dan Shao,4,5 Jing Qiu,1,2 Ming Li,1,2 Xiao Zheng,5 Yun Xiao,6 Zheng Wang,4 Zhi-min Chang,4 Li Chen,5 Wen-fei Dong,4 Chun-bo Tang1,2 1Department of Oral Implantology, Affiliated Hospital of Stomatology, Nanjing Medical ...
Qiu J, Lu M, Dong W, Zheng X, Xiao Y, Chen L, Tang C, Bai J, Chang Z, Wang Z, Shao D, Li M   +11 more
core