Results 151 to 160 of about 39,888 (323)

Percutaneous transhepatic obliteration with N-butyl-2-cyanoacrylate in a patient with a superior mesenteric vein intraluminal distal small bowel variceal bleed

open access: yesInternational Journal of Gastrointestinal Intervention
Gastrointestinal (GI) bleeding is a serious complication with a high mortality rate (45%-55%) that can result from a variety of conditions, including portal hypertension, diverticulosis, or splenic vein thrombosis.
William Henry Eskew   +2 more
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Tissue Adhesives in Reconstructive and Aesthetic Surgery-Application of Silk Fibroin-Based Biomaterials. [PDF]

open access: yesInt J Mol Sci, 2022
Smeets R   +13 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Cyanoacrylate Tissue Adhesives – Effective Securement Technique for Intravascular Catheters: In Vitro Testing of Safety and Feasibility [PDF]

open access: bronze, 2012
Gabriela Šimonová   +5 more
openalex   +1 more source

Robust tetra‐armed poly (ethylene glycol)‐based hydrogel as tissue bioadhesive for the efficient repair of meniscus tears

open access: yesMedComm
Repair and preservation of the injured meniscus has become paramount in clinical practice. However, the complexities of various clinic stitching techniques for meniscus repair pose challenges for grassroots doctors.
Jing Ye   +9 more
doaj   +1 more source

In vivo measurement of afferent activity with axon-specific calcium imaging. [PDF]

open access: yes, 2018
In vivo calcium imaging from axons provides direct interrogation of afferent neural activity, informing the neural representations that a local circuit receives.
Broussard, Gerard Joey   +8 more
core  

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