Results 51 to 60 of about 38,488 (345)

Thyroid Hormone as a Method of Reducing Damage to Donor Hearts after Circulatory Arrest [PDF]

, 2017
There is a chronic lack of donor hearts to meet the need for heart transplant both in the US and worldwide. Further, the use of available hearts is limited by the short period between collection and implantation during which the heart can be safely ...
Adams, William P.
core   +1 more source

Assessment of Organ and Tissue Procurement Knowledge in Health Care Workers Associated to Critical and Emergency Care Units

Salud Uninorte, 2022
Objetivo: Evaluar el nivel de conocimiento de profesionales en salud frente a la donación de órganos y tejidos en Barranquilla. Metodología: Estudio de corte transversal con encuesta semiestructurada sobre el conocimiento de la donación de órganos y tejidos en el personal de salud entre junio hasta diciembre de 2019. Se incluyen 232 profesionales de la
Katty Álvarez-Manduca, Nasly Patino-Jaramillo, Andrea García-Lopéz, Fernando Girón-Luque   +3 more
openaire   +2 more sources

Oral Streptococcus salivarius Couples Neutrophil IRGM1 Signaling to NET Formation and Colorectal Cancer Metastasis

Advanced Science, EarlyView.
The oral bacterium Streptococcus salivarius promotes colorectal cancer metastasis by inducing neutrophil extracellular trap (NET) formation. Mechanistically, IRGM1–IQGAP1 interaction activates Wnt5a–PI3K/AKT signaling in neutrophils, driving NET‐mediated tumor progression.
Fengyi Liu, Yuan Wang, Hengxuan Cai, Qianwen Yue, Xueli Liu, Xuanwen Bao, Zeng Wang, Xuehan Li, Lai Wei, Zhihua Zhang, Fan Xing, Yi Xu, Xianjun Li, Wei Xu   +13 more
wiley   +1 more source

Francisella tularensis Transmission by Solid Organ Transplantation, 20171. [PDF]

, 2019
In July 2017, fever and sepsis developed in 3 recipients of solid organs (1 heart and 2 kidneys) from a common donor in the United States; 1 of the kidney recipients died.
Annambhotla, Pallavi, Asad, Shadaba, Aslam, Saima, Basavaraju, Sridhar V, Brown, Jennifer, Burns, Kevin, Carifo, Karen, Dagher, Hikmat N, Fritz, Curtis L, Gonzalez, Anthony, Ham, John, Helsel, Elizabeth, Hinckley, Alison F, Iser, Joseph, Johnson, Michael, Jones, Jefferson M, Kelley, Walter E, Kingry, Luke C, Krafft, Melissa, Kwit, Natalie A, Medina-Garcia, Luis H, Mohler, Kelli, Murua, Christian, Nelson, Christina A, Petersen, Jeannine M, Respicio-Kingry, Laurel, Tularemia in Transplant Recipients Investigation Team, Wiggins, Landon, Zhang, Ying   +28 more
core  

Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis

Advanced Science, EarlyView.
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou, Yongfeng Chen, Longyou Xiao, Wei Qi, Tianshu Du, Qiang Sun, Borui Xue, Qinghe Zhao, Pengfei Xie, Zi Ye, Fei Han, Lingli Guo, Yang Jiao, Ranran Zhang, Hong Jia, Xiao Huang, Jianwei Guo, Peng Wang, Huayi Wang, Yuanrui Wang, Wenjing Chen, Haining Wu, Liumin He, Dawei Zhang   +23 more
wiley   +1 more source

Autonomia na doação de órgãos post mortem no Brasil

Revista Bioética
Resumo Desde 1964, ano da primeira lei brasileira de doação de órgãos, muitos avanços da medicina aumentaram a qualidade e expectativa de vida, dentre eles o aprimoramento das técnicas de transplante.
Willian Pimentel, Marcelo Sarsur, Luciana Dadalto   +2 more
doaj   +1 more source

Can adenine nucleotides predict primary nonfunction of the human liver homograft? [PDF]

, 1994
Sixty-eight primary liver grafts were analyzed to see whether adenine nucleotides (AN: ATP, ADP, and AMP) or purine catabolites (PC: adenosine, inosine, hypoxanthine, and xanthine) of tissue or effluent can predict primary graft nonfunction.
Bronsther, O, Fujita, S, Hamamoto, I, Irish, W, Nakamura, K, Starzl, TE, Takaya, S, Todo, S, Van Gulik, TM   +8 more
core   +1 more source

A local, non-commercial tissue bank connected to an organ donor program can produce musculoskeletal allografts of uniform quality at very low costs – ten years’ experience

Cell and Tissue Banking
It is common practice that allograft tissues for knee multiligament reconstruction, meniscus transplantation, cartilage replacement and other advanced procedures are made available through commercial banks.
Helia Azkia, L. Harritshøj, Connie Nielsen, Niels Agerlin, M. G. Jensen, Jens G Hillingsø, P. C. Andersen, M. Krogsgaard   +7 more
semanticscholar   +1 more source

A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project

Biopreservation and Biobanking, 2015
The Genotype-Tissue Expression (GTEx) project, sponsored by the NIH Common Fund, was established to study the correlation between human genetic variation and tissue-specific gene expression in non-diseased individuals.
Latarsha J. Carithers, K. Ardlie, M. Barcus, P. Branton, Angela Britton, Stephen A. Buia, C. Compton, D. DeLuca, Joanne Peter-Demchok, Ellen T. Gelfand, P. Guan, G. Korzeniewski, N. Lockhart, C. Rabiner, Abhi Rao, Karna L. Robinson, Nancy V. Roche, Sherilyn J. Sawyer, A. Segrè, C. Shive, Anna M. Smith, L. Sobin, Anita H. Undale, Kimberly M. Valentino, J. Vaught, Taylor R. Young, Helen M. Moore   +26 more
semanticscholar   +1 more source

Hierarchical Targeting of TREM2+ Myeloid Cells via Acid‐Triggered OMVs Reprogram Immunosuppression and Suppress Osteolysis in Bone‐Metastatic TNBC

Advanced Science, EarlyView.
This study developed a hierarchical targeting nanoplatform, siTREM2@ETP‐PEOz‐OMVs, against triple‐negative breast cancer (TNBC) bone metastasis. It precisely delivers therapeutic siTREM2 to monocytes/macrophages within the metastatic niche. This intervention dually regulates cell fate: reprogramming immunosuppressive macrophages and inhibiting ...
Fanglu Chen, Yucheng Xue, Xiao Ma, Liang Chen, Zhenxuan Shao, Hangxiang Sun, Haochen Mou, Fangqian Wang, Zilong Li, Yechao Shen, Zhaoming Ye, Xiaohua Yu, Shengdong Wang   +12 more
wiley   +1 more source