Results 71 to 80 of about 36,410 (330)

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

Advanced Science, EarlyView.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li, Yanjie Guo, Jianlin Li, Yimeng Li, Leqian Lin, Hoi Kit Matthew Leung, Qingqing Zhang, Kai‐Fai Lee, Ka‐Wang Cheung, Ernest H. Y. Ng, William S. B. Yeung, Philip C. N. Chiu, Cheuk‐Lun Lee   +12 more
wiley   +1 more source

Compte-rendu de The Kidney Sellers: A Journey of Discovery in Iran par Sigrid Fry-Revere – Response by the author

BioéthiqueOnline, 2014
In response to the review by Allard and Fortin, this paper offers a few clarifications regarding the author’s book.
Fry-Revere, Sigrid
doaj  

Understanding the dynamics of deceased organ donation and utilization in Colombia

Revista Panamericana de Salud Pública
Objective. To obtain a comprehensive overview of organ donation, organ utilization, and discard in the entire donation process in Colombia. Methods. A retrospective study of 1 451 possible donors, distributed in three regions of Colombia, evaluated in ...
William Cruz Mususú, Andrea García-Lopez, Nicolás Lozano-Suarez, Andrea Gómez-Montero, Milena Orellano-Salas, Luisa Vargas-Pérez, Ximena Escobar-Chaves, Fernando Girón-Luque   +7 more
doaj   +1 more source

Australian perioperative nurses’ attitudes, levels of knowledge, education and support needs related to organ donation and procurement surgery: A national survey

Journal of Perioperative Nursing, 2019
Objectives: The aim of this study was to examine Australian perioperative nurses’ self-reported knowledge, attitudes, levels of education and support in relation to their participation in organ donation and procurement surgery.
Zaneta Smith, Cindy Woods, Jackie Lea, Kim Usher   +3 more
doaj   +1 more source

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

Advanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang, Zhichao Li, Tianci Hu, Qinyao Li, Linwei Zhang, Xinyue Mei, Xiao Qi, Sheng Liu, Weijie Kong, Jiesi Luo, Anguo Wu, Feihong Huang, Sirui Li, Shuang Dai, Chunxiang Zhang, Rong Li, Jianming Wu   +16 more
wiley   +1 more source

Donar, un cambio de vida: comprender la experiencia de familiares que aceptaron la donación de órganos [PDF]

, 2014
Indexación: Web of Science; Scielo.Background: Most organ donors are already death. Therefore family members become an essential link in the final decision for organ donation.
Avilés R., Lissette, Catoni S., , María Isabel, Rivera M., Soledad   +2 more
core  

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

Consent Model, Opt-in/Opt-out System, and Organ Donation Rates in European Union Countries

Applied Medical Informatics, 2020
Introduction:Disparities in organ donation rates exists through the world countries, even despite sharing a common legislative background. The model of the consent for organ donation after brain death (deceased donor) informed consent (opt-in system) or ...
Petru COTRĂU, Viviana HODOSAN, Adriana VLADU, Lucia DAINA, Marcel NEGRĂU, Cristian DAINA, Carmen PANTIŞ, Corina VERNIC   +7 more
doaj  

Beyond Catalytic Therapy: Copper‐Paeonol Nanozymes Disrupt Fascin‐Mediated Actin Bundling to Suppress Tumor Growth and Metastasis

Advanced Science, EarlyView.
Copper‐paeonol nanozymes target tumor‐specific reactive oxygen species generation and disrupt fascin‐mediated actin bundling, effectively suppressing tumor growth and metastatic colonization. Abstract Fascin, an actin‐bundling protein universally upregulated in metastatic tumors, drives tumor migration and invasion by promoting filopodia and ...
Peiying Zhang, Huajun Li, Yisen Wang, Jie Xiang, Lei Fan, Shengzhe Zhang, Lizeng Gao, Hua Dai, Juqun Xi   +8 more
wiley   +1 more source

Family interview for organ and tissue donation: good practice assumptions

Revista Brasileira de Enfermagem
Objectives: to identify information that can support creating good practice assumptions to develop family interview for organ and tissue donation. Methods: this scoping study, conducted in two Brazilian hospitals in the southern, between April and ...
Neide da Silva Knhis, Sabrina Regina Martins, Aline Lima Pestana Magalhães, Saulo Fábio Ramos, Camila Telemberg Sell, Clarice Koerich, Laura Calvacanti de Farias Brehmer   +6 more
doaj   +2 more sources