Results 81 to 90 of about 61,211 (254)

Screening for PPAR Non-Agonist Ligands Followed by Characterization of a Hit, AM-879, with Additional No-Adipogenic and cdk5-Mediated Phosphorylation Inhibition Properties

open access: yesFrontiers in Endocrinology, 2018
Peroxisome proliferator-activated receptor gamma (PPARγ) is a member of a nuclear receptor superfamily and acts as a ligand-dependent transcription factor, playing key roles in maintenance of adipose tissue and in regulation of glucose and lipid ...
Helder Veras Ribeiro Filho   +14 more
doaj   +1 more source

Observation of anisotropic diffusion of light in compacted granular porous materials

open access: yes, 2011
It is known that compaction of granular matter can lead to anisotropic mechanical properties. Recent work has confirmed the link to pore space anisotropy, but the relation between compression, mechanical properties and material microstructure remains ...
Alerstam, Erik, Svensson, Tomas
core   +1 more source

Magnetothermal‐Triggered Response and Self‐Healing of Recyclable and Reprocessable Nanocomposites for Actuation Systems

open access: yesAdvanced Functional Materials, EarlyView.
Developing recyclable materials for magnetic robotics that combine rapid response and self‐healing properties is challenging. Hence, this study focuses on the integration of magnetothermal nanoparticles into a dynamic sorbitol‐based vitrimer, a recyclable composite capable of remote actuation and self‐healing by magnetic heating.
Maria Weißpflog   +3 more
wiley   +1 more source

Impact of uniaxial cyclic stretching on matrix-associated endothelial cell responses

open access: yesMaterials Today Bio
Uniaxial cyclic stretching plays a pivotal role in the fields of tissue engineering and regenerative medicine, influencing cell behaviors and functionality based on physical properties, including matrix morphology and mechanical stimuli.
Cuihong Ren   +7 more
doaj   +1 more source

Blood Perfusion and Cellular Microstructural Changes Associated With Iron Deposition in Multiple Sclerosis Lesions

open access: yesFrontiers in Neurology, 2019
Background and Purpose: Susceptibility-weighted imaging (SWI) has emerged as a useful clinical tool in many neurological diseases including multiple sclerosis (MS).
Huaqiang Sheng   +3 more
doaj   +1 more source

Light‐Actuated Fiber‐Climbing Inchworm Robot Toward Endoluminal Navigation

open access: yesAdvanced Functional Materials, EarlyView.
A kirigami‐inspired soft inchworm robot harnesses optical energy from a customized side‐emitting optical fiber, guaranteeing its propulsion along the fiber body. The wavelength‐selective responsiveness of dye‐functionalized liquid crystal elastomers and the application of temporal illumination patterns enable sequential control of robot components. The
Antonio Lobosco   +6 more
wiley   +1 more source

Sliding contact loading enhances the tensile properties of mesenchymal stem cell-seeded hydrogels [PDF]

open access: yesEuropean Cells & Materials, 2012
The primary goal of cartilage tissue engineering is to recapitulate the functional properties and structural features of native articular cartilage.
AH Huang   +3 more
doaj  

Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling

open access: yesAdvanced Healthcare Materials, EarlyView.
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee   +7 more
wiley   +1 more source

Tract profiles of white matter properties: automating fiber-tract quantification.

open access: yesPLoS ONE, 2012
Tractography based on diffusion weighted imaging (DWI) data is a method for identifying the major white matter fascicles (tracts) in the living human brain.
Jason D Yeatman   +4 more
doaj   +1 more source

Designing bio-mimetic variational porosity for tissue scaffolds [PDF]

open access: yes, 2012
Reconstructing or repairing the damaged or diseased tissues with porous scaffolds to restore the mechanical, biological and chemical functions is one of the major tissue engineering strategies.
Khoda, AKM   +2 more
core  

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