Results 81 to 90 of about 178,041 (308)

Agrobiodiversity and Its Conservation in Nepal [PDF]

, 2020
Nepal is a part of the world\u27s biodiversity hotspot and ranks the 49th in the world for biodiversity. Agrobiodiversity and its conservation status were studied through literature review, field survey, key informant survey and focus group discussion ...
Ghimire, K. H. (Krishna), Gorkhali, N. A. (Neena), Gotame, T. P. (Tek), Joshi, B. K. (Bal), Karkee, A. (Ajaya), KC, P. (Prenil), Mainali, R. P. (Ram), Paneru, R. B. (Ram), Pradhan, N. (Neeta)   +8 more
core  

Biosamples as gifts? How participants in biobanking projects talk about donation. [PDF]

, 2015
Funded by National Institute for Health Research (NIHR) Oxford Biomedical Research Centre based at Oxford University Hospitals NHS Trust University of Oxford Oxford Biomedical Research Centre FellowshipPeer reviewedPublisher ...
Andrews, Barr, Cragg Ross Dawson, Dixon-Woods, Dixon-Woods, Gaskell, Haddow, Haimes, Hoeyer, Hoeyer, Kanellopoulou, Kaye, Laurie, Lenk, Lipworth, Locock, Manson, Mauss, Medical Research Council, Nuffield Council on Bioethics, OECD, People Science and Policy Ltd, Primary Care Reports, Scheper-Hughes, Seale, Solbakk, Titmuss, Tutton, Tutton, Waldby, Walsh, Widdows, Widdows   +32 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Postoperative detection of unusual pathology in donor corneal tissue

Indian Journal of Ophthalmology, 2019
We present a series of three patients with previously undetected corneal pathology in grafted corneal tissue following keratoplasty for keratoconus. Postoperatively, a faint layer of anterior stromal haze involving the graft was observed in each patient ...
Louis J Stevenson, Graeme Pollock, Rasik B Vajpayee   +2 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

cGMP-Manufactured Human Induced Pluripotent Stem Cells Are Available for Pre-clinical and Clinical Applications

Stem Cell Reports, 2015
The discovery of induced pluripotent stem cells (iPSCs) and the concurrent development of protocols for their cell-type-specific differentiation have revolutionized our approach to cell therapy.
Behnam Ahmadian Baghbaderani, Xinghui Tian, Boon Hwa Neo, Amy Burkall, Tracy Dimezzo, Guadalupe Sierra, Xianmin Zeng, Kim Warren, Don Paul Kovarcik, Thomas Fellner, Mahendra S. Rao   +10 more
doaj   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Setting up clinical and production-based biobanks in the healthcare system of the Russian Federation

Трансплантология (Москва)
Background. The therapeutic efficacy of skin grafts and various tissue equivalents in the treatment of many diseases is known. Special clinical biobanks are engaged in the procurement of such products, their processing, storage, provision of their safety
Yu. N. Lebedeva, Yu. V. Sukhanov, E. M. Fominykh, A. V. Eremeev, O. S. Rogovaya, T. A. Aleksanyan, E. A. Vorotelyak, A. V. Vasiliev   +7 more
doaj   +1 more source

Influence of submerged macrophytes on phosphorus in a eutrophic reservoir in a semiarid region

Journal of Limnology, 2020
Phosphorus (P) is the main nutrient responsible for the harmful effects caused by the enrichment of aquatic systems, and submerged macrophytes play an important role in this process, since they can both remove and release this nutrient in environmental ...
Vanessa Virginia Barbosa, Juliana dos Santos Severiano, Dayany Aguiar de Oliveira, José Etham de Lucena Barbosa   +3 more
doaj   +1 more source

Von Economo Neuron Loss in Frontotemporal Dementia: A Meta‐Analysis of Neuropathological Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Von Economo neurons (VENs) have been reported to be vulnerable to neurodegeneration in frontotemporal dementia (FTD), particularly the behavioral variant (bvFTD), but these findings have not been systematically assessed across independent brain banks.
Daniel Talmasov, Alexander F. Santillo, Patrick R. Hof   +2 more
wiley   +1 more source