Results 101 to 110 of about 2,270,440 (301)

Histone H3K18 Lactylation Promotes the Malignant Progression of Wilms Tumor via a PSRC1/AKT/HIF‐1α Positive Feedback Loop

Advanced Science, EarlyView.
In nephroblastoma, aberrant glycolysis drives lactate accumulation, which elevates histone H3K18 lactylation via p300. Lactylation of the PSRC1 promoter activates its transcription. PSRC1 competitively binds AKT, relieving PTEN‐mediated inhibition and triggering AKT/mTOR/HIF‐1α signaling.
Yanping Wang, Hongjie Gao, Bifei Zhang, Xuetian Li, Ding Li, Aihua Cao, Fengyin Sun   +6 more
wiley   +1 more source

Tissue banking.

The Western journal of medicine, 1991
The Scientific Board of the California Medical Association presents the following inventory of items of progress in orthopedics. Each item, in the judgment of a panel of knowledgeable physicians, has recently become reasonably firmly established, both as to scientific fact and important clinical significance.
openaire   +3 more sources

Norges Banks oppgjørssystem (NBO) : Tjenester for bankene og staten : Årsrapport 2007 [PDF]

, 2008
Formålet med Norges Banks oppgjørssystem (NBO) er å gjennomføre sikre og effektive oppgjør av betalinger mellom banker som har konto i Norges Bank.

core  

Hollow Cu2O Nanozymes Enhance Probiotic Therapy for Colitis via Redox Homeostasis and TXNIP/NLRP3 Inflammasome Inhibition

Advanced Science, EarlyView.
Hollow cuprous oxide (H‐Cu2O) nanozymes feature enlarged catalytic surfaces for superior reactive oxygen species (ROS) scavenging. By efficiently neutralizing mucosal ROS, H‐Cu2O directly suppresses the TXNIP/NLRP3 inflammasome axis and restores intestinal epithelial barrier integrity.
Guangzhao Wang, Jialing Cao, Pengfei Li, Yujie Wang, Shiqi Lu, Kangliang Sheng, Shan Gao, Yongzhong Wang   +7 more
wiley   +1 more source

The Expression of Androgen Receptor and Its Variants in Human Prostate Cancer Tissue according to Disease Status, and Its Prognostic Significance

The World Journal of Men's Health, 2019
Purpose: To evaluate changes in the expression of androgen receptor (AR) and its variants (ARVs) in human prostate cancer (PCa) tissues according to disease status, and its prognostic significance following radical prostatectomy (RP).
Sung-Woo Park, Jung Hee Kim, Hyun Jung Lee, Dong Hoon Shin, Sang Don Lee, Sik Yoon   +5 more
doaj   +1 more source

A test of the herbivore optimization hypothesis using muskoxen and a graminoid meadow plant community

Rangifer, 1996
A prediction from the herbivore optimization hypothesis is that grazing by herbivores at moderate intensities will increase net above-ground primary productivity more than at lower or higher intensities. I tested this hypothesis in an area of high muskox
David L. Smith
doaj   +1 more source

Adipose derived tissue engineered heart valve [PDF]

, 2015
Introduction: A major challenge associated with heart valve tissue engineering is the in vitro creation of mature tissue structures compliant with native valve functionality.
Baaijens, FPT Frank, Beer, G M, Driessen - Mol, A., Hoerstrup, S., Beer, G.M., Baaijens, Frank P T, Baaijens, F.P.T., Weber, B., Hoerstrup, S P, Driessen-Mol, Anita, Frese, Laura, Frese, L., Driessen-Mol, A Anita, Weber, Benedikt, Beer, Gertrude M, Sanders, B Bart, Hoerstrup, S Simon, Sanders, Bart, Sanders, B.   +18 more
core   +2 more sources

ZBTB11 Promotes Breast Cancer Progression by Activating FBXO28‐Mediated MST1 Degradation and Suppressing Hippo Signaling

Advanced Science, EarlyView.
ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu, Xiang‐Nan Xu, Xiao Huang, Zhou Luo, Chun‐Lian Li, Yang Du, Cheng Yan, Xiao‐Jie Yu, Jian‐Wen Wang, Long‐Di Yao, De‐Yuan Fu   +10 more
wiley   +1 more source

Spiral Tissue Microarrays as Next Evolutionary Step in the High-density Tissue Microarray Technology [PDF]

, 2010
Tissue microarray (TMA) is a well-established technique that connects basic research with clinical applications that allow the validation of many pathobiologic events from gene expression dysregulation to genomic aberrations.
Junya Fukuoka, Matthias Hofer, Tomonori Tanaka, Takeshi Uemura, Lucian Chirieac, Sayaka Tominaga, Takashi Hori, Ryo Ohsawa   +7 more
core  

Disrupting Helicobacter pylori Iron Homeostasis With Bismuth Nanodrug‐Mediated Nutritional Trap for Targeted Gastric Infection Therapy

Advanced Science, EarlyView.
A “nutritional trap” strategy centered on disrupting bacterial iron homeostasis is proposed. The synthesized Bi‐TP@FU (TBF) can target Helicobacter pylori, interfere with the bacterial iron uptake and utilization processes to disrupt its iron homeostasis, induce bacterial death, and meanwhile preserve the balance of the intestinal flora.
Tianye Fang, Jinzhe Tong, Feng Feng, Cong Liu, Chang Shu, Jiaying Zhu, Shibo Zhang, Shuyue Deng, Wanchao Zuo, Yuhan Song, Jun Yang, Yanmin Ju, Yingying Xing, Jianjun Dai   +13 more
wiley   +1 more source