Results 91 to 100 of about 177,664 (273)

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Adhesive and degradative properties of human placental cytotrophoblast cells in vitro. [PDF]

open access: yes, 1989
Human fetal development depends on the embryo rapidly gaining access to the maternal circulation. The trophoblast cells that form the fetal portion of the human placenta have solved this problem by transiently exhibiting certain tumor-like properties ...
Cui, TY   +7 more
core   +3 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Protocol for Imaging and Analysis of Mouse Tumor Models with CUBIC Tissue Clearing

open access: yesSTAR Protocols, 2020
Summary: Tissue-clearing technologies have developed rapidly in the past decade, especially for use in neuroscience research. We previously reported that CUBIC, which is one tissue-clearing method, is useful for applications in cancer research.
Kei Takahashi   +4 more
doaj   +1 more source

Rationalisation and Validation of an Acrylamide-Free Procedure in Three-Dimensional Histological Imaging. [PDF]

open access: yesPLoS ONE, 2016
Three-dimensional visualization of intact tissues is now being achieved by turning tissues transparent. CLARITY is a unique tissue clearing technique, which features the use of detergents to remove lipids from fixed tissues to achieve optical ...
Hei Ming Lai   +11 more
doaj   +1 more source

The characteristic time of glucose diffusion measured for muscle tissue at optical clearing [PDF]

open access: yes, 2013
The study of agent diffusion in biological tissues is very important to understand and characterize the optical clearing effects and mechanisms involved: tissue dehydration and refractive index matching.
Carvalho, M I   +3 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Optimizing tissue clearing and imaging methods for human brain tissue

open access: yesJournal of International Medical Research, 2021
Objectives To identify optimum sample conditions for human brains, we compared the clearing efficiency, antibody staining efficiency, and artifacts between fresh and cadaver samples.
Min Sun Kim   +6 more
doaj   +1 more source

Optical clearing of vaginal tissues in cadavers [PDF]

open access: yesTherapeutics and Diagnostics in Urology 2018, 2018
A nonsurgical laser procedure is being developed for treatment of female stress urinary incontinence (SUI). Previous studies in porcine vaginal tissues, ex vivo, as well as computer simulations, showed the feasibility of using near-infrared laser energy delivered through a transvaginal contact cooling probe to thermally remodel endopelvic fascia, while
Chun-Hung, Chang   +6 more
openaire   +2 more sources

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