Results 151 to 160 of about 2,147,918 (389)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

FDG kinetics in cells and tissues: a biochemically-driven compartmental approach [PDF]

open access: yesarXiv, 2018
The radioactive glucose analogue 2-deoxy-2-[18F]fluoro-D-glucose (FDG) is widely used to reconstruct glucose metabolism and other biological functions in cells and tissues. The analysis of data on the time course of FDG tracer distribution is performed by the use of appropriate compartmental models.
arxiv  

Cell and Tissue Culture

open access: yesThe American Journal of the Medical Sciences, 1960
Cell and tissue culture , Cell and tissue culture , مرکز فناوری اطلاعات و اطلاع رسانی ...
openaire   +2 more sources

A retrotransposon-based-strategy for the assessment of genetic and epigenetic stability of oil palm embryogenic suspensions [PDF]

open access: yes, 2012
Clonal regenerants of oil palm (Elaeis guineensis Jacq) can display a detrimental variant phenotype called mantled which affects the floral morphology of adult palms thus lowering oil yields in clonal offspring.
Beulé, Thierry   +7 more
core  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy