Results 171 to 180 of about 9,392,969 (335)

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Himalayan fermented beverages and their therapeutic properties with scientific validations: a comprehensive review

Journal of Ethnic Foods
The Himalayan ethnoecology revolves around a balanced relationship between harsh mountain environment and the diverse lifestyles of its ethnic communities, where traditional knowledge on medicinal plants and fermented foods plays important role in their ...
Soumya Majumder, Malay Bhattacharya
doaj   +1 more source

Subcutaneous Phycomycosis in a Child [PDF]

, 2009
Subcutaneous phycomycosis is a rare entity. We hereby report a case of subcutaneous phycomycosis in 18 months old female child who presented with a painless, non-tender swelling on the thigh.
Jagtap, SV, Naniwadekar, MR, Nikam, BP, Sanghavi, KD   +3 more
core  

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

In vitro regeneration of plantlets from nodal explants of Aristolochia saccata and Aristolochia cathcartii

European Journal of Biological Research, 2017
In vitro propagation of Aristolochia saccata and A. cathcartii were carried out using nodal explant. In both the plants, nodal explants showed direct somatic embryogenesis when cultured on MS medium using various concentrations of BAP (1.0-4.0) and 2iP ...
Bhaskar Sarma, Bhaben Tanti
doaj  

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Morphological and molecular identification of endophytic fungi from roots of epiphyte orchid Aerides odorata Lour in Sabah

Scientific Reports
Aerides odorata Lour is an epiphyte, a valuable orchid for its beauty, fragrance and medicinal uses. Identifying beneficial orchid mycorrhizal fungi is important for improving the success of tissue culture and transplantation into the original habitats ...
Nor Amirah Shamsudin, Jaya Seelan Sathiya Seelan, Jualang Azlan Gansau, Nor Azizun Rusdi   +3 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Cost-effective nutrient sources for tissue culture of cassava (Manihot esculenta Crantz)

, 2012
Kwame Ogero
openalex   +1 more source