Results 101 to 110 of about 12,729,869 (376)

Selective Tissue Distribution Mediates Tissue-Dependent PPARγ Activation and Insulin Sensitization by INT131, a Selective PPARγ Modulator

open access: yesFrontiers in Pharmacology, 2017
The mechanisms underlying the enhancement of insulin sensitivity by selective peroxisome proliferator-activated receptor γ modulators (sPPARγMs) are still not completely known.
Xinni Xie   +15 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Toxicokinetics and Tissue Distribution of the Hepatotoxic Triterpenoid Saponin Pterocephin A in Rats Using the Ultra-Performance Liquid Chromatography–Tandem Mass Spectrometry (UPLC-MS/MS) Method

open access: yesMolecules
Pterocephin A is a natural triterpenoid saponin isolated from Pterocephalus hookeri, a traditional Tibetan medicine with slight toxicity, which can induce liver injury in rats.
Yiran Xiong   +8 more
doaj   +1 more source

Subchronic inhalation toxicity of gold nanoparticles

open access: yesParticle and Fibre Toxicology, 2011
Background Gold nanoparticles are widely used in consumer products, including cosmetics, food packaging, beverages, toothpaste, automobiles, and lubricants.
Chung Yong   +15 more
doaj   +1 more source

Transport of secondary electrons and reactive species in ion tracks

open access: yes, 2015
The transport of reactive species brought about by ions traversing tissue-like medium is analysed analytically. Secondary electrons ejected by ions are capable of ionizing other molecules; the transport of these generations of electrons is studied using ...
Solov'yov, Andrey V.   +1 more
core   +1 more source

Tissue multifractality and Born approximation in analysis of light scattering: a novel approach for precancers detection [PDF]

open access: yes, 2014
Multifractal, a special class of complex self-affine processes, are under recent intensive investigations because of their fundamental nature and potential applications in diverse physical systems.
Ch Ivanov Plamen   +20 more
core   +1 more source

Distribution of Myrosinase in Rapeseed Tissues [PDF]

open access: yesPlant Physiology, 1991
Immunocytochemical studies on Brassica napus (rapeseed) tissues using a monoclonal antibody against myrosinase (thioglucoside glucohydrolase) showed that the enzyme was only present in a small number of cells. In the developing embryo, scattered myrosinase-containing cells were present in both cotyledons and axis.
A S, Höglund   +3 more
openaire   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Persistent Contamination of Octopuses and Mussels with Lipophilic Shellfish Toxins during Spring Dinophysis Blooms in a Subtropical Estuary

open access: yesMarine Drugs, 2015
This study investigates the occurrence of diarrhetic shellfish toxins (DSTs) and their producing phytoplankton species in southern Brazil, as well as the potential for toxin accumulation in co-occurring mussels (Perna perna) and octopuses (Octopus ...
Luiz L. Mafra   +4 more
doaj   +1 more source

On the use of the Bingham statistical distribution in microsphere-based constitutive models for arterial tissue [PDF]

open access: yes, 2010
Constitutive models for arterial tissue have been an active research field during the last years. The main micro-constituents of blood vessels are different types of cells and the extra-cellular matrix formed by an isotropic high water content ground ...
Alastrué, V.   +3 more
core   +2 more sources

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