Results 141 to 150 of about 7,939,784 (316)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Consumption of Zinc Biofortified Rice Diet Improved Mineral Availability: An Approach to Address Micronutrient Malnutrition

Foods
Zinc (Zn), a micronutrient, plays vital roles in various biological functions and its inadequate intake results in various clinical manifestations. Biofortification of staple crops through breeding approaches has been attempted to ensure a higher dietary
Natesan Ramachandran, Marappan Gopi, Duraisamy Rajendran, Dintaran Pal, Balakrishnan Binsila, Madhusoodanan N. Unnikrishnan, Chirravuri N. Neeraja, Gundallahalli B. Manjunatha Reddy, Arindam Dhali, Sudhir Chandra Roy, Ashish Mishra, Kaliappan Bharathi, Jeeva Mutthu Kumar, Artabandhu Sahoo, Raghavendra Bhatta   +14 more
doaj   +1 more source

The Impasse of Post Keynesian Distribution Theory

, 1992
Why did the topic of income distribution loose its attraction for the economic profession? The article analyzes the structure of the Ricardian theory and of the post-Keynesian approach and discusses the question why after Pasinetti’s contribution ...
Thomasberger, C.
core  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Insight into Cd Detoxification and Accumulation in Wheat by Foliar Application of Ferulic Acid

Plants
Cadmium (Cd) contamination in agricultural soils poses a significant threat to human health through the food chain. It is of great significance to address safe wheat production in Cd-contaminated agricultural soils. This study employed foliar spraying of
Simeng Li, Wenyang Fu, Bingling Li, Yi Wang, Yiran Cheng, Houyang Kang, Jian Zeng   +6 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Uptake, Elimination and Metabolism of Brominated Dibenzofurans in Mice

Toxics
Polybrominated dibenzofurans (PBDFs) are major brominated dioxins in the environment, but information on their bioaccumulation potential and toxicokinetics is limited.
Nguyen Minh Tue, Eiki Kimura, Fumihiko Maekawa, Akitoshi Goto, Naoto Uramaru, Tatsuya Kunisue, Go Suzuki   +6 more
doaj   +1 more source

Consumption, Income Distribution and Taxation: Keynes’ Fiscal Policy

, 1998
The General Theory argued that income distribution affected consumption. Greater income inequality put more money into the hands of people with higher MPCs, leading to increased consumption; and inequality had the reverse impact.
Pressman, Steven
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source