Results 261 to 270 of about 3,131,990 (302)

Tissue Distribution of Methylenedioxymethamphetamine

Journal of Analytical Toxicology, 1992
Two cases of death involving methylenedioxymethamphetamine (MDMA) are reported; one case is a fatal acute overdose and the other is a drug-related death. The tissue distribution of MDMA is reported in both cases.
T P, Rohrig, R W, Prouty
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Distribution of hydrocarbons in bovine tissues

Lipids, 1979
AbstractLiver, heart, kidneys, muscle and adipose (perirenal and subcutaneous) tissues were collected from six animals for analysis of their hydrocarbon composition. Qualitative and quantitative determinations were carried out by gas chromatography and combined gas chromatography‐mass spectrometry.
C, Lintas, A M, Balduzzi, M P, Bernardini, A, Di Muccio   +3 more
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Tissue distribution of clenbuterol in the horse

Journal of Veterinary Pharmacology and Therapeutics, 2004
Plasma and tissue concentrations of clenbuterol (CLB) were determined following oral (p.o.) administration of 1.6 μg/kg twice daily (b.i.d.) for 2 weeks. Horses were administered the last dose on morning of day 15, killed at 0.25, 24, 48, and 72 h post‐administration. At 0.25 h, the highest tissue concentrations of CLB were found in the liver (16.21 ng/
L R, Soma, C E, Uboh, F, Guan, Y, Luo, D, Teleis, L, Runbo, E K, Birks, D S, Tsang, P, Habecker   +8 more
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Hexachlorobenzene distribution in tissues of swine

Toxicology and Applied Pharmacology, 1979
Abstract Purified hexachlorobenzene (HCB) was administered to third-litter sows at dietary concentrations of 0, 1, or 20 ppm throughout gestation and nursing. Swine receiving 1 ppm were not adversely affected and residue concentrations in tissues other than fat and bone marrow remained at or below the dietary concentration.
L G, Hansen, J, Simon, S B, Dorn, R H, Teske   +3 more
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Tissue Distribution of Primaquine in the Rat

Pharmacology, 1981
The distribution of primaquine was measured in seven rat tissues at 15-180 min after the intraperitoneal injection of the antimalarial 8-aminoquinoline. The half-life of unmetabolized primaquine was 4.0 h in lung, 1.7-1.9 h in blood, spleen, kidney and heart, and 1.2 h in liver.
D J, Holbrook, J B, Griffin, L, Fowler, B R, Gibson   +3 more
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Tissue distribution of roxithromycin

Journal of Antimicrobial Chemotherapy, 1987
As tissue distribution studies have become increasingly important aspects of the assessment of new antimicrobials, roxithromycin distribution has been evaluated in experimental models and in human tissues and body fluids. High levels were achieved in respiratory tract tissues and fluids and in the male and female genital tract.
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Distribution of Selenium in the Tissues of the Eye

Nature, 1966
FOR the past few years we have been investigating the presence and distribution of selenium in the normal and dystrophic state1,2. The biological role of selenium is as yet unknown; however, the physical and chemical properties of the element are well established.
H H, Taussky, A, Washington, E, Zubillaga, A T, Milhorat   +3 more
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The importance of tissue distribution in pharmacokinetics

Journal of Pharmacokinetics and Biopharmaceutics, 1972
In evoking pharmacological and toxicological responses, drugs generally combine either reversibly or irreversibly with action sites on intrastitial macromolecules or organelles, and thereby cause alterations of physico-chemical or biochemical processes in the living animal. These alterations can be evoked by a number of mechanisms.
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Distribution of ceftazidime in rat tissues

Biopharmaceutics & Drug Disposition, 1998
The pharmacokinetics and tissue distribution of ceftazidime (CFT), a third generation cephalosporin antibiotic commonly used in clinical practice, were investigated in rats after intravenous administration of the antibiotic. Studies using intravenous bolus administration were carried out at two dose levels (5 and 20 mg) of the antibiotic.
L, Granero, J, Chesa-Jiménez, F, Torres-Molina, J E, Peris   +3 more
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