Tissue Determinants of Human NK Cell Development, Function, and Residence. [PDF]
Immune responses in diverse tissue sites are critical for protective immunity and homeostasis. Here, we investigate how tissue localization regulates the development and function of human natural killer (NK) cells, innate lymphocytes important for anti ...
Arakawa-Hoyt, Janice+16 more
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Omental adipose tissue is a more suitable source of canine Mesenchymal stem cells [PDF]
Background: Mesenchymal Stem Cells (MSCs) are a promising therapeutic tool in veterinary medicine. Currently the subcutaneous adipose tissue is the leading source of MSCs in dogs.
Bahamondes, Francisca+4 more
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Who should be prioritized for renal transplantation?: Analysis of key stakeholder preferences using discrete choice experiments [PDF]
Background Policies for allocating deceased donor kidneys have recently shifted from allocation based on Human Leucocyte Antigen (HLA) tissue matching in the UK and USA. Newer allocation algorithms incorporate waiting time as a primary factor, and in
A Allepuz+38 more
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Synovial tissue macrophages: friend or foe? [PDF]
Healthy synovial tissue includes a lining layer of synovial fibroblasts and macrophages. The influx of leucocytes during active rheumatoid arthritis (RA) includes monocytes that differentiate locally into proinflammatory macrophages, and these produce ...
Alivernini, Stefano+1 more
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Renal transplantation at the university of Colorado [PDF]
From March 1962 to April 1963, 118 patients were treated with renal transplantation, 3 with kidneys from identical twins, 9 with cadaveric homografts, and 106 with homografts from volunteer donors.
Brettschneider, L+6 more
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Transplantation of the heart after circulatory death of the donor: time for a change in law? [PDF]
Procurement of organs has always been conducted according to the dead donor rule, that is, after death of the donor — but this practice is being challenged. Introduction Australia has an increasing shortfall in transplantable hearts.
James Tibballs, Neera Bhatia
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"Suboptimal" kidney donors: The experience with tacrolimus-based immunosuppression [PDF]
Female, pediatric, and older donors have been associated with inferior graft survival after renal transplantation. We analyzed these three subgroups in 397 patients receiving tacrolimus-based immunosuppression. There were no differences in recipient age,
Alexander+23 more
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Soluble pre-fibrillar tau and β-amyloid species emerge in early human Alzheimer’s disease and track disease progression and cognitive decline [PDF]
Acknowledgments We would like to gratefully acknowledge all donors and their families for the tissue provided for this study. Human tissue samples were supplied by the Brains for Dementia Research programme, jointly funded by Alzheimer’s Research UK, the
Cranston, Anna+5 more
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The lady vanishes: what's missing from the stem cell debate [PDF]
Most opponents of somatic cell nuclear transfer and embryonic stem cell technologies base their arguments on the twin assertions that the embryo is either a human being or a potential human being, and that it is wrong to destroy a human being or ...
A. Fagot-Largeault+50 more
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Gay and bisexual men’s perceptions of the donation and use of human biological samples for research: a qualitative study [PDF]
Human biological samples (biosamples) are increasingly important in diagnosing, treating and measuring the prevalence of illnesses. For the gay and bisexual population, biosample research is particularly important for measuring the prevalence of human ...
Hilton, Shona+2 more
core +3 more sources