A perfusion culture system for assessing bone marrow stromal cell differentiation on PLGA scaffolds for bone repair [PDF]
, 2018 Biomaterials development for bone repair is currently hindered by the lack of physiologically relevant in vitro testing systems. Here we describe the novel use of a bi-directional perfusion bioreactor to support the long term culture of human bone marrow
Alini, Mauro +5 more
core +2 more sources
Gay and bisexual men’s perceptions of the donation and use of human biological samples for research: a qualitative study [PDF]
, 2015 Human biological samples (biosamples) are increasingly important in diagnosing, treating and measuring the prevalence of illnesses. For the gay and bisexual population, biosample research is particularly important for measuring the prevalence of human ...
Hilton, Shona +2 more
core +7 more sources
Archives of Academic Emergency Medicine, 2018 Introduction:Â Organ donation is one of the surviving procedures which can increase the life expectancy of end-stage patients. Inappropriate beliefs and attitude of individuals to organ donation, their poor knowledge, and the socio-economic level are one
Mahboob Pouraghaei +5 more
doaj +1 more source
Distinct blood and visceral adipose tissue regulatory T cell and innate lymphocyte profiles characterize obesity and colorectal cancer [PDF]
, 2017 Visceral adipose tissue (VAT) is a main site where metabolic and immunologic processes interplay to regulate, at local and systemic level, the inflammatory status and immune response.
Barbara Varano +14 more
core +2 more sources
Multiscreen serum analysis of highly sensitized renal dialysis patients for antibodies toward public and private class I HLA determinants: Implications for computer-predicted acceptable and unacceptable donor mismatches in kidney transplantation [PDF]
, 1990 A multiscreen serum analysis program has been developed that permits a determination of antibody specificity for the vast majority of highly sensitized patients awaiting transplantation.
Banner, BF +6 more
core +1 more source
Living unrelated donor kidney transplantation: A fourteen-year experience [PDF]
Vojnosanitetski Pregled, 2010 Background. In countries without a national organization for retrieval and distribution of organs of the deceased donors, problem of organ shortage is still not resolved.
Ignjatović Ljiljana +64 more
doaj +1 more source
Substance Use Affects Type 1 Diabetes Pancreas Pathology: Implications for Future Studies
Frontiers in Endocrinology, 2021 Access to human pancreas samples from organ donors has greatly advanced our understanding of type 1 diabetes pathogenesis; however, previous studies have shown that donors have a high rate of substance use, and its impact on pancreatic histopathology in ...
Brittany S. Bruggeman +13 more
doaj +1 more source
Tensin1 expression and function in chronic obstructive pulmonary disease [PDF]
, 2019 open access articleChronic obstructive pulmonary disease (COPD) constitutes a major cause of morbidity and mortality. Genome wide association studies have shown significant associations between airflow obstruction or COPD with a non-synonymous SNP in ...
Amrani, Y. +7 more
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Novel, cross-restricted, conserved, and immunodominant Cytotoxic T Lymphocyte epitopes in slow progressors in HIV Type 1 infection [PDF]
, 1996 HIV-specific cytotoxic T lymphocytes (CTLs) play an important role in the immune response to HIV infection. Long-term nonprogressors (LTNPs) or slow progressors (SPs) in HIV infection may make qualitatively different CTL responses compared to those ...
ANDREW J. McMICHAEL +12 more
core +2 more sources
Francisella tularensis Transmission by Solid Organ Transplantation, 2017
Emerging Infectious Diseases, 2019 In July 2017, fever and sepsis developed in 3 recipients of solid organs (1 heart and 2 kidneys) from a common donor in the United States; 1 of the kidney recipients died.
Christina A. Nelson +27 more
doaj +1 more source