Results 111 to 120 of about 443,290 (307)

Low rate of detection of SARS-CoV-2 RNA in deceased tissue donors. [PDF]

Cell Tissue Bank, 2023
Greenwald MA, Grebe E, Green V, Jones AL, Linnen JM, Williamson P, Busch MP, Kuehnert MJ.   +7 more
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Understanding the dynamics of deceased organ donation and utilization in Colombia

Revista Panamericana de Salud Pública
Objective. To obtain a comprehensive overview of organ donation, organ utilization, and discard in the entire donation process in Colombia. Methods. A retrospective study of 1 451 possible donors, distributed in three regions of Colombia, evaluated in ...
William Cruz Mususú, Andrea García-Lopez, Nicolás Lozano-Suarez, Andrea Gómez-Montero, Milena Orellano-Salas, Luisa Vargas-Pérez, Ximena Escobar-Chaves, Fernando Girón-Luque   +7 more
doaj   +1 more source

Musculoskeletal Tissue Banking in Singapore: 15 Years of Experience (1988–2003)

Journal of Orthopaedic Surgery, 2004
Purpose. To report 15 years' experience of musculoskeletal tissue banking by the National University Hospital Tissue Bank. Methods. This study describes the development of Singapore's national bone bank since its establishment in 1988.
A Nather
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Human tooth bank: sociocultural profile of a group of donors [PDF]

RGO: Revista Gaúcha de Odontologia, 2010
Objective: To survey the sociocultural profile of a specific group of individuals who donated teeth to the Human Tooth Bank of Positivo University, Curitiba, Paraná, Brazil.
Mariane Moreira Poletto, Mônica Moreira, Marília Moreira Dias, Maria da Graça Kfouri Lopes, Osmir José Lavoranti, Eduardo Pizzatto   +5 more
doaj  

COVID-19 positivity rate in corneal tissue donors - A cause for concern! [PDF]

Indian J Ophthalmol, 2021
D'Souza S, Shetty R, Kundu G, Sharma N, Tandon R, Matalia H, Gorimanipalli B, Jayadev C.   +7 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Maternal and fetal outcomes of pregnancies in kidney donors: A 30-year comparative analysis of matched non-donors in a single center

Kidney Research and Clinical Practice, 2018
Background : Woman kidney donors face obstetric complication risks after kidney donation, such as gestational hypertension and preeclampsia. Studies on childbirth-related complications among Asian women donors are scarce.
Kyung Don Yoo, Hajeong Lee, Yaerim Kim, Sehoon Park, Joong Shin Park, Joon Seok Hong, Chang Wook Jeong, Hyeon Hoe Kim, Jung Pyo Lee, Dong Ki Kim, Kook-Hwan Oh, Kwon Wook Joo, Yon Su Kim   +12 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source