Results 261 to 270 of about 439,003 (336)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Long-term fixation impact on archived human nervous tissues for sequencing-based transcriptomics. [PDF]

Brain Commun
Howe S, McCann H, Xiong Z, Nguyen Q, Steyn FJ, Ngo ST, Chang J.   +6 more
europepmc   +1 more source

Use of Preimplantation Diagnosis to Produce Tissue Donors: An Irreconcilable Dichotomy

, 2003
Colin Gavaghan
openalex   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Strategic insights into organ donation: perceptions, attitudes, and the impact of disincentive removal in current and future medical professionals. [PDF]

Front Public Health
Arizmendi-Villarreal MA, Ugalde-Flores AC, Sanchez-Maldonado J, Flores-Mendoza AP, Zapata-Chavira HA, Muñoz-Maldonado GE, Perez-Rodriguez E, Reyna-Sepulveda FJ.   +7 more
europepmc   +1 more source

The free vascularised iliac crest tissue transfer: donor site complications associated with eighty-two cases

, 1992
Chris Forrest, Brian Boyd, Ralph T. Manktelow, Ron M. Zuker, V.T. Bowen   +4 more
openalex   +1 more source

Planning for End-of-Life Health Care Decisions--What National Survey Results Reveal [PDF]

, 2006
Whitton, Linda S.
core   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Mapping CMV-related immune signatures in blood, aorta and perivascular mediastinal adipose tissue. [PDF]

Philos Trans R Soc Lond B Biol Sci
Labeb C, Obare LM, Sheng Q, Zhang X, Gangula R, Nthenge K, Bailin SS, Mashayekhi M, Stephens VR, Stolze L, Priest S, Malone JC, Oakes JM, Gabriel CL, Phillips EJ, Kalams SA, Mallal SA, Gianella S, Koethe JR, Su YR, Absi T, Wanjalla CN.   +21 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source