Results 21 to 30 of about 437,420 (241)

Myocardial aging as a T-cell–mediated phenomenon [PDF]

, 2017
In recent years, the myocardium has been rediscovered under the lenses of immunology, and lymphocytes have been implicated in the pathogenesis of cardiomyopathies with different etiologies.
Abeßer, Marco, Beyersdorf, Niklas, Burkard, Matthias, Frantz, Stefan, Friedrich, Mike, Heinze, Katrin G., Hofmann, Ulrich, Jocelyne, Demengeot, Kerkau, Thomas, Nunes-Silva, Vânia, Peters, Laura, Pinnecker, Jürgen, Ramos, Gustavo Campos, Schuh, Kai, van den Berg, Anne, Weirather, Johannes   +15 more
core   +1 more source

Biobanks: Conservation of the humanity scientific heritage

Iatreia, 2022
A biobank allows the collections of biological samples to be maintained in optimal conditions and in an organized manner with the highest quality, ethical and legal standards, for biomedical research purposes that generate new knowledge, as well as ...
Chalarca-Cañas, David, Vargas-Tejada, Daniel Andrés, Valencia-Ocampo, Oscar Jairo, Velásquez-Lopera, Margarita María   +3 more
doaj   +1 more source

Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection. [PDF]

, 2020
The primary reservoir for HIV is within memory CD4+ T cells residing within tissues, yet the features that make some of these cells more susceptible than others to infection by HIV is not well understood.
Cavrois, Marielle, Deeks, Steven G, Frouard, Julie, Gramatica, Andrea, Greene, Warner C, Hoh, Rebecca, Hsiao, Feng, Jones, R Brad, Lee, Guinevere Q, Lee, Sulggi, Luo, Xiaoyu, Roan, Nadia R, Roychoudhury, Pavitra, Schwarzer, Roland, Telwatte, Sushama, Xie, Guorui, Yukl, Steven A   +16 more
core   +1 more source

Soluble pre-fibrillar tau and β-amyloid species emerge in early human Alzheimer’s disease and track disease progression and cognitive decline [PDF]

, 2016
Acknowledgments We would like to gratefully acknowledge all donors and their families for the tissue provided for this study. Human tissue samples were supplied by the Brains for Dementia Research programme, jointly funded by Alzheimer’s Research UK, the
Cranston, Anna, Gardner, Heidi, Jones, Glynn, Kanaan, Nicholas M., Koss, David J., Platt, Bettina   +5 more
core   +3 more sources

Essential Role of Lyn in Fibrosis. [PDF]

, 2016
Fibrotic disorders involve replacement of normal parenchyma with myofibroblasts, which deposit connective tissue, leading to obliteration of the function of the underlying organ.
Birtolo, Chiara, Chheda, Chintan, Cirulli, Vincenzo, Gugliotta, Gabriele, Lewis, Michael S, Liu, Sandy T, Pandol, Stephen J, Pham, Hung, Ptasznik, Andrzej, Rodriguez, Maria D, Yang, Wendy   +10 more
core   +2 more sources

Hypoxic pre-conditioning increases the infiltration of endothelial cells into scaffolds for dermal regeneration pre-seeded with mesenchymal stem cells. [PDF]

, 2015
Many therapies using mesenchymal stem cells (MSC) rely on their ability to produce and release paracrine signals with chemotactic and pro-angiogenic activity.
Beegle, Julie R, Chávez, Myra N, Egaña, José T, Fierro, Fernando A, Isseroff, Roslyn R, O'Neal, Adam J, Peavy, Thomas R   +6 more
core   +2 more sources

Effect of a reduction in glomerular filtration rate after nephrectomy on arterial stiffness and central hemodynamics: rationale and design of the EARNEST study [PDF]

, 2014
Background: There is strong evidence of an association between chronic kidney disease (CKD) and cardiovascular disease. To date, however, proof that a reduction in glomerular filtration rate (GFR) is a causative factor in cardiovascular disease is ...
Alam, Arena, Bahous, Benetos, Blacher, Blacher, Boudville, Briet, Charles J. Ferro, Charles R. Tomson, Chue, Chue, Daniel Zehnder, DeLoach, Doucende, Edwards, Eknoyan, Faul, Fehrman-Ekholm, Foley, Forbat, Frimodt-Moller, Garg, Go, Groenink, Grothues, Guerin, Hametner, Ian B. Wilkinson, Ibrahim, Jackson, John R. Cockcroft, Jonathan N. Townend, Kasiske, Krohn, Landray, Lang, Laurent, Laurie A. Tomlinson, Levey, Lewington, Luzardo, Maceira, Madero, Mafham, Mark, Martensson, Matsushita, Michels, Moody, Moody, Myerson, Nagueh, National Kidney Foundation, O'Brien, Patrick B. Mark, Richard P. Steeds, Rook, Rothwell, Savage, Schiffrin, Schiller, Segev, Tavakol, Townsend, Vickery, Wang, Wei, Weiss, Wiesmann, Wilkinson, William E. Moody, Yeon, Young   +73 more
core   +2 more sources

Knowledge, Attitude and Willingness Towards Organ Donation among People Attending Out Patient Departments of a Tertiary Care Hospital, West Bengal: A Cross-sectional Study [PDF]

Journal of Caring Sciences
Introduction: Organ donation rate in India is lower compared to many developed countries. A shortage of organs for individuals in need persists, as people are hesitant to donate.
Bobby Syiemlieh, Obangkokla O, Mousumi Khatun, Poonam Joshi, Latha T, Jamuna R Rani, Ajay Mallick   +6 more
doaj   +1 more source

Knowledge and Attitude Regarding Organ Donation among Relatives of Patients Referred to the Emergency Department

Archives of Academic Emergency Medicine, 2018
Introduction: Organ donation is one of the surviving procedures which can increase the life expectancy of end-stage patients. Inappropriate beliefs and attitude of individuals to organ donation, their poor knowledge, and the socio-economic level are one
Mahboob Pouraghaei, Mohammad Tagizadieh, Ali Tagizadieh, Payman Moharamzadeh, Samaneh Esfahanian, kavous Shahsavari Nia   +5 more
doaj   +1 more source

Public views on the donation and use of human biological samples in biomedical research: a mixed methods study [PDF]

, 2013
Objective A mixed methods study exploring the UK general public's willingness to donate human biosamples (HBSs) for biomedical research.<p></p> Setting Cross-sectional focus groups followed by an online survey.<p></p> ...
Clotworthy, M., Corfield, J., Hilton, S., Lewis, C., MaGee, C., Robertson, M.J., Stubbins, L.J.   +6 more
core   +1 more source