Hypoxic pre-conditioning increases the infiltration of endothelial cells into scaffolds for dermal regeneration pre-seeded with mesenchymal stem cells. [PDF]
Many therapies using mesenchymal stem cells (MSC) rely on their ability to produce and release paracrine signals with chemotactic and pro-angiogenic activity.
Beegle, Julie R +6 more
core +2 more sources
Substance Use Affects Type 1 Diabetes Pancreas Pathology: Implications for Future Studies
Access to human pancreas samples from organ donors has greatly advanced our understanding of type 1 diabetes pathogenesis; however, previous studies have shown that donors have a high rate of substance use, and its impact on pancreatic histopathology in ...
Brittany S. Bruggeman +13 more
doaj +1 more source
Living unrelated donor kidney transplantation: A fourteen-year experience [PDF]
Background. In countries without a national organization for retrieval and distribution of organs of the deceased donors, problem of organ shortage is still not resolved.
Ignjatović Ljiljana +64 more
doaj +1 more source
Multi-Parameter Analysis of Biobanked Human Bone Marrow Stromal Cells Shows Little Influence for Donor Age and Mild Comorbidities on Phenotypic and Functional Properties [PDF]
Heterogeneous populations of human bone marrow-derived stromal cells (BMSC) are among the most frequently tested cellular therapeutics for treating degenerative and immune disorders, which occur predominantly in the aging population.
Andrzejewska, Anastazja +22 more
core +1 more source
A perfusion culture system for assessing bone marrow stromal cell differentiation on PLGA scaffolds for bone repair [PDF]
Biomaterials development for bone repair is currently hindered by the lack of physiologically relevant in vitro testing systems. Here we describe the novel use of a bi-directional perfusion bioreactor to support the long term culture of human bone marrow
Alini, Mauro +5 more
core +2 more sources
Tensin1 expression and function in chronic obstructive pulmonary disease [PDF]
open access articleChronic obstructive pulmonary disease (COPD) constitutes a major cause of morbidity and mortality. Genome wide association studies have shown significant associations between airflow obstruction or COPD with a non-synonymous SNP in ...
Amrani, Y. +7 more
core +1 more source
A New Skin Graft Donor Site Using the Abdominal Dog-Ear Deformity in Mastectomy Flap Necrosis [PDF]
Background Mastectomy flap necrosis is a common complication after mastectomy and immediate reconstruction with a deep inferior epigastric perforator (DIEP) flap. After abdominal free flap breast reconstruction, the most common secondary procedure is dog-
Jong Hyun Choi, Deuk Young Oh
doaj +1 more source
Corneal Donor Tissue Preparation for Endothelial Keratoplasty [PDF]
Over the past ten years, corneal transplantation surgical techniques have undergone revolutionary changes. Since its inception, traditional full thickness corneal transplantation has been the treatment to restore sight in those limited by corneal disease.
Woodward, Maria A. +3 more
openaire +2 more sources
The lady vanishes: what's missing from the stem cell debate [PDF]
Most opponents of somatic cell nuclear transfer and embryonic stem cell technologies base their arguments on the twin assertions that the embryo is either a human being or a potential human being, and that it is wrong to destroy a human being or ...
A. Fagot-Largeault +50 more
core +2 more sources
Francisella tularensis Transmission by Solid Organ Transplantation, 2017
In July 2017, fever and sepsis developed in 3 recipients of solid organs (1 heart and 2 kidneys) from a common donor in the United States; 1 of the kidney recipients died.
Christina A. Nelson +27 more
doaj +1 more source

