Results 31 to 40 of about 4,783,918 (377)

Aluminium in human brain tissue from donors without neurodegenerative disease: A comparison with Alzheimer’s disease, multiple sclerosis and autism

open access: yesScientific Reports, 2020
A burgeoning number of studies are demonstrating aluminium in human brain tissue. While research has both quantified and imaged aluminium in human brain tissue in neurodegenerative and neurodevelopmental disease there are few similar data for brain ...
C. Exley, Elizabeth Clarkson
semanticscholar   +1 more source

Cross-tissue immune cell analysis reveals tissue-specific features in humans

open access: yesScience, 2022
Despite their crucial role in health and disease, our knowledge of immune cells within human tissues remains limited. We surveyed the immune compartment of 16 tissues from 12 adult donors by single-cell RNA sequencing and VDJ sequencing generating a ...
C. Domínguez Conde   +40 more
semanticscholar   +1 more source

Nurses' challenges in caring for an organ donor brain dead patient and their solution strategies: A systematic review

open access: yesIranian Journal of Nursing and Midwifery Research, 2020
Background: Caring for brain dead patient is one of the most troublous duties of an Intensive Care Unit (ICU) nurse. This study aimed to determine nursing challenges based on recent literature and identify the strategies to overcome these challenges ...
Hamideh YazdiMoghaddam   +2 more
doaj   +1 more source

The Significance of the Nucleic Acid Test (NAT) to Prevent Viral Contamination in Musculoskeletal Tissue Transplantation

open access: yesRevista Brasileira de Ortopedia, 2023
Objective The present study aims to highlight the significance of the nucleic acid test (NAT) for musculoskeletal tissue donation and to compare the sensitivity of this test on the different available platforms.
Carlos Alexandre Curylofo Corsi   +7 more
doaj   +2 more sources

Pancreas tissue slices from organ donors enable in situ analysis of type 1 diabetes pathogenesis.

open access: yesJCI Insight, 2020
In type 1 diabetes (T1D), autoimmune destruction of pancreatic β cells leads to insulin deficiency and loss of glycemic control. However, knowledge about human pancreas pathophysiology in T1D remains incomplete. To address this limitation, we established
J. Panzer   +19 more
semanticscholar   +1 more source

Profile of effective organ and tissue donors from a north-northeast referral hospital [PDF]

open access: yesRevista Enfermagem Digital Cuidado e Promoção da Saúde, 2019
Objective: To characterize the profile of effective organ and tissue donors in a referral hospital in the northnortheast.Methods: This is a descriptive, cross-sectional study with a quantitative approach, based on secondary data from organ and tissue ...
Aline Mércia Nunes Teixeira   +6 more
doaj   +1 more source

Critical pathway for deceased donors: An analysis in three regions of Colombia

open access: yesRevista Colombiana de Cirugía, 2023
Introduction. The critical pathway for deceased donation offers a methodical framework for guiding the donation process. It not only serves to assess performance but also to identify areas of potential improvement.
William Cruz-Mususú   +7 more
doaj   +1 more source

Profiling Microglia From Alzheimer’s Disease Donors and Non-demented Elderly in Acute Human Postmortem Cortical Tissue

open access: yesFrontiers in Molecular Neuroscience, 2020
Microglia are the tissue-resident macrophages of the central nervous system (CNS). Recent studies based on bulk and single-cell RNA sequencing in mice indicate high relevance of microglia with respect to risk genes and neuro-inflammation in Alzheimer’s ...
Astrid M Alsema   +17 more
semanticscholar   +1 more source

Dynamical System Modeling to Simulate Donor T Cell Response to Whole Exome Sequencing-Derived Recipient Peptides: Understanding Randomness in Clinical Outcomes Following Stem Cell Transplantation [PDF]

open access: yesPLoS One. 2017 Dec 1;12(12):e0187771, 2016
Alloreactivity following stem cell transplantation (SCT) is difficult to predict in patients undergoing transplantation from HLA matched donors. In this study we performed whole exome sequencing of SCT donor-recipient pairs (DRP). This allowed determination of entire library of alloreactive peptide sequences which would bind HLA class I molecules in ...
arxiv   +1 more source

Evaluation of Two Enzyme-Linked Immunosorbent Assay Kits for Chikungunya Virus IgM Using Samples from Deceased Organ and Tissue Donors

open access: yesClinical and Vaccine Immunology, 2016
The identification of nearly 3,500 cases of chikungunya virus (CHIKV) infection in U.S. residents returning in 2014 and 2015 from areas in which it is endemic has raised concerns within the transplant community that, should recently infected individuals ...
H. Prince, M. Altrich, M. Nowicki
semanticscholar   +1 more source

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