Results 41 to 50 of about 4,738,879 (420)

Dynamical System Modeling to Simulate Donor T Cell Response to Whole Exome Sequencing-Derived Recipient Peptides: Understanding Randomness in Clinical Outcomes Following Stem Cell Transplantation [PDF]

PLoS One. 2017 Dec 1;12(12):e0187771, 2016
Alloreactivity following stem cell transplantation (SCT) is difficult to predict in patients undergoing transplantation from HLA matched donors. In this study we performed whole exome sequencing of SCT donor-recipient pairs (DRP). This allowed determination of entire library of alloreactive peptide sequences which would bind HLA class I molecules in ...
arxiv   +1 more source

Neonatal donation:are newborns too young to be recognized? [PDF]

, 2021
Neonatal organ and tissue donation is not common practice in the Netherlands. At the same time, there is a transplant waiting list for small size-matched organs and tissues. Multiple factors may contribute to low neonatal donation rates, including a lack
Baptist, Dyvonne H., Hulzebos, Christian V., Siebelink, Marion J., Toet, Mona C., Verhagen, Eduard A. A., Vileito, Alicija   +5 more
core   +1 more source

P07-A139 Guttae in corneal donor tissue

EEBA 2023 Session I – Tissue banking: Lamellar Grafts; Corneal Storage Methods; Quality Assurance, 2023
To report on the occurrence of guttae in corneal donor tissue.Retrospective database study of discard reasons for corneal donor tissue at Amnitrans EyeBank Rotterdam (AER) for the period from January 2019 to December 2021 and the outcome of an eight-question survey sent to European Eye Bank Association corresponding members addressing the occurrence of
Groeneveld-van Beek, Esther A, Lie, Jessica T, Claessens, Simone A, Sajet, Anita, Dedeci, Mehtap, Herdt, Louise De, Melles, Gerrit Rj, Kocaba, Viridiana, Oellerich, Silke, Wees, Jacqueline van der   +9 more
openaire   +3 more sources

Cross-tissue immune cell analysis reveals tissue-specific features in humans

Science, 2022
Despite their crucial role in health and disease, our knowledge of immune cells within human tissues remains limited. We surveyed the immune compartment of 16 tissues from 12 adult donors by single-cell RNA sequencing and VDJ sequencing generating a ...
C. Domínguez Conde, C. Xu, LB Jarvis, DB Rainbow, SB Wells, T. Gomes, S. Howlett, O. Suchanek, K. Polański, HW King, L. Mamanova, N. Huang, PA Szabo, L. Richardson, L. Bolt, ES Fasouli, K. Mahbubani, M. Prete, L. Tuck, N. Richoz, Z. Tuong, L. Campos, HS Mousa, EJ Needham, S. Pritchard, T. Li, R. Elmentaite, J. Park, E. Rahmani, D. Chen, D. Menon, O. Bayraktar, L. James, K. Meyer, N. Yosef, M. Clatworthy, Patrick C. Sims, DL Farber, K. Saeb‐Parsy, Jl Jones, S. Teichmann   +40 more
semanticscholar   +1 more source

Francisella tularensis Transmission by Solid Organ Transplantation, 2017

Emerging Infectious Diseases, 2019
In July 2017, fever and sepsis developed in 3 recipients of solid organs (1 heart and 2 kidneys) from a common donor in the United States; 1 of the kidney recipients died.
Christina A. Nelson, Christian Murua, Jefferson M. Jones, Kelli Mohler, Ying Zhang, Landon Wiggins, Natalie A. Kwit, Laurel Respicio-Kingry, Luke C. Kingry, Jeannine M. Petersen, Jennifer Brown, Saima Aslam, Melissa Krafft, Shadaba Asad, Hikmat N. Dagher, John Ham, Luis H. Medina-Garcia, Kevin Burns, Walter E. Kelley, Alison F. Hinckley, Pallavi Annambhotla, Karen Carifo, Anthony Gonzalez, Elizabeth Helsel, Joseph Iser, Michael Johnson, Curtis L. Fritz, Sridhar V. Basavaraju   +27 more
doaj   +1 more source

Soluble pre-fibrillar tau and β-amyloid species emerge in early human Alzheimer’s disease and track disease progression and cognitive decline [PDF]

, 2016
Acknowledgments We would like to gratefully acknowledge all donors and their families for the tissue provided for this study. Human tissue samples were supplied by the Brains for Dementia Research programme, jointly funded by Alzheimer’s Research UK, the
Cranston, Anna, Gardner, Heidi, Jones, Glynn, Kanaan, Nicholas M., Koss, David J., Platt, Bettina   +5 more
core   +2 more sources

Attitudes and motives of potential sperm donors in Serbia [PDF]

Vojnosanitetski Pregled, 2012
Background/Aim. For curing infertility, sperm donors and their donations are important source of benefits for the society. Attitudes of sperm donors towards different recipient categories and relation with offspring become more important.
Hedrih Anđelka, Hedrih Vladimir
doaj   +1 more source

Endothelial keratoplasty with infant donor tissue

Clinical Ophthalmology, 2014
Here we report a case of endothelial keratoplasty with infant donor tissue obtained after brain death. A 52-year-old man with endothelial dysfunction of unknown cause in the right eye underwent non-Descemet stripping automated endothelial keratoplasty (nDSAEK) with tissue from an infant donor (2 years).
Hideaki Yokogawa, Kazuhisa Sugiyama, Natsuko Yamazaki, Akira Kobayashi, Toshinori Masaki   +4 more
openaire   +5 more sources

Nurses' challenges in caring for an organ donor brain dead patient and their solution strategies: A systematic review

Iranian Journal of Nursing and Midwifery Research, 2020
Background: Caring for brain dead patient is one of the most troublous duties of an Intensive Care Unit (ICU) nurse. This study aimed to determine nursing challenges based on recent literature and identify the strategies to overcome these challenges ...
Hamideh YazdiMoghaddam, Zahra-Sadat Manzari, Eesa Mohammadi   +2 more
doaj   +1 more source

Substance Use Affects Type 1 Diabetes Pancreas Pathology: Implications for Future Studies

Frontiers in Endocrinology, 2021
Access to human pancreas samples from organ donors has greatly advanced our understanding of type 1 diabetes pathogenesis; however, previous studies have shown that donors have a high rate of substance use, and its impact on pancreatic histopathology in ...
Brittany S. Bruggeman, Brittany S. Bruggeman, Martha Campbell-Thompson, Martha Campbell-Thompson, Stephanie L. Filipp, Matthew J. Gurka, Mark A. Atkinson, Mark A. Atkinson, Mark A. Atkinson, Desmond A. Schatz, Desmond A. Schatz, Desmond A. Schatz, Laura M. Jacobsen, Laura M. Jacobsen   +13 more
doaj   +1 more source