Results 41 to 50 of about 439,003 (336)

Metabotropic glutamate receptor 2/3 (mGluR2/3) activation suppresses TRPV1 sensitization in mouse, but not human sensory neurons [PDF]

, 2018
The use of human tissue to validate putative analgesic targets identified in rodents is a promising strategy for improving the historically poor translational record of preclinical pain research.
Baranger, David A.A., Gereau, Robert W, McIlvried, Lisa V, Pullen, Melanie Y, Sheahan, Tayler D, Valtcheva, Manouela V   +5 more
core   +2 more sources

Francisella tularensis Transmission by Solid Organ Transplantation, 2017

Emerging Infectious Diseases, 2019
In July 2017, fever and sepsis developed in 3 recipients of solid organs (1 heart and 2 kidneys) from a common donor in the United States; 1 of the kidney recipients died.
Christina A. Nelson, Christian Murua, Jefferson M. Jones, Kelli Mohler, Ying Zhang, Landon Wiggins, Natalie A. Kwit, Laurel Respicio-Kingry, Luke C. Kingry, Jeannine M. Petersen, Jennifer Brown, Saima Aslam, Melissa Krafft, Shadaba Asad, Hikmat N. Dagher, John Ham, Luis H. Medina-Garcia, Kevin Burns, Walter E. Kelley, Alison F. Hinckley, Pallavi Annambhotla, Karen Carifo, Anthony Gonzalez, Elizabeth Helsel, Joseph Iser, Michael Johnson, Curtis L. Fritz, Sridhar V. Basavaraju   +27 more
doaj   +1 more source

Barriers to the identification of possible organ donors among brain-injured patients admitted to intensive care units

Korean Journal of Transplantation, 2023
Background : Improving organ donation rates requires better detection of possible organ donors, which in turn necessitates identifying barriers preventing the identification of possible organ donors.
Abdul Jabbar bin Ismail, Nor Diyanah Ahmad, Chong Si Ching, Cheah Siew Lean, Tony Tan Beng Keong, Mohd Izzwan Zaini, Cheah Phee Kheng   +6 more
doaj   +1 more source

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li, Ronghua Hong, Hua You, Feiping Xu, Qingjun Zhang, Yiwen Lin, Yuting Su, Danmei Lan, Lingjing Jin, Junhui She   +9 more
wiley   +1 more source

The Anticipated Organ Donation Approach Increases the Number of Organ Donors

Turkish Journal of Anaesthesiology and Reanimation
Objective: Deficiency of organs for transplantation is a significant public health issue. French learned societies accept intensive care unit admission for patients with catastrophic neurological prognosis to optimize organs prior to probable brain death.
Erwan d’Aranda, Valérie Arsonneau, Didier Demory   +2 more
doaj   +1 more source

KIR2DL2/2DL3-E(35) alleles are functionally stronger than -Q(35) alleles. [PDF]

, 2016
KIR2DL2 and KIR2DL3 segregate as alleles of a single locus in the centromeric motif of the killer cell immunoglobulin-like receptor (KIR) gene family. Although KIR2DL2/L3 polymorphism is known to be associated with many human diseases and is an important
Bao, Ju, Bari, Rafijul, Leung, Wing, Li, Ying, Thapa, Rajoo, Zheng, Jie   +5 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Cellular Characteristics and Protein Signatures of Human Adipose Tissues from Donors With or Without Advanced Coronary Artery Disease

Biomedicines
Background/Objectives: Perivascular adipose tissue (PVAT) exerts a paracrine effect on blood vessels and our objective was to understand PVAT molecular signatures related to cardiovascular disease.
Caitlin P. S. Ellis, Benjamin W. Tero, Christian M. Potts, Kimberly T. Malka, Xuehui Yang, Joshua Hamilton, Calvin Vary, Andre Khalil, Lucy Liaw   +8 more
doaj   +1 more source

A New Skin Graft Donor Site Using the Abdominal Dog-Ear Deformity in Mastectomy Flap Necrosis [PDF]

Archives of Aesthetic Plastic Surgery, 2018
Background Mastectomy flap necrosis is a common complication after mastectomy and immediate reconstruction with a deep inferior epigastric perforator (DIEP) flap. After abdominal free flap breast reconstruction, the most common secondary procedure is dog-
Jong Hyun Choi, Deuk Young Oh
doaj   +1 more source

Commercialisation of the supply of organs for transplantation [PDF]

, 2001
Internationally, there is a shortage of organs available for organ donation. Human tissue and cells are becoming increasingly valuable as part of commercially valuable biotechnological research.
Thomas, Cordelia
core