Results 71 to 80 of about 443,290 (307)

Growth factors for clinical-scale expansion of human articular chondrocytes : Relevance for automated bioreactor systems [PDF]

, 2007
The expansion of chondrocytes in automated bioreactors for clinical use requires that a relevant number of cells be generated, starting from variable initial seeding densities in one passage and using autologous serum.
Andrea Barbero, Cherubino P., Christian Candrian, Christina-Priska Sie, Eloit M, Gobbi A., Ivan Martin, Michael Heberer, Roberto Tommasini, Rupert Hagg, Silvia-Elena Francioli, Watt F.M, Wessman S.J.   +12 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Mini-Laparoscopic Donor Nephrectomy

Urology Journal, 2012
No ...
Nasser Simforoosh, Mohammad Hossein Soltani, Ali Ahanian   +2 more
doaj  

Biosamples as gifts? How participants in biobanking projects talk about donation. [PDF]

, 2015
Funded by National Institute for Health Research (NIHR) Oxford Biomedical Research Centre based at Oxford University Hospitals NHS Trust University of Oxford Oxford Biomedical Research Centre FellowshipPeer reviewedPublisher ...
Andrews, Barr, Cragg Ross Dawson, Dixon-Woods, Dixon-Woods, Gaskell, Haddow, Haimes, Hoeyer, Hoeyer, Kanellopoulou, Kaye, Laurie, Lenk, Lipworth, Locock, Manson, Mauss, Medical Research Council, Nuffield Council on Bioethics, OECD, People Science and Policy Ltd, Primary Care Reports, Scheper-Hughes, Seale, Solbakk, Titmuss, Tutton, Tutton, Waldby, Walsh, Widdows, Widdows   +32 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Donor-derived cell-free DNA predicted allograft rejection and severe microvascular inflammation in kidney transplant recipients

Frontiers in Immunology
IntroductionThe aim of this study is to investigate the clinical validity of donor-derived cell-free DNA (dd-cfDNA) in comparison with that of donor specific anti-HLA antibody (DSA) for predicting biopsy-proven rejection (BPR)and severe microvascular ...
Hyung Duk Kim, Hyunjoo Bae, Hyunhye Kang, Hyunhye Kang, Hanbi Lee, Sang Hun Eum, Chul Woo Yang, Yeong Jin Choi, Byung Ha Chung, Eun-Jee Oh, Eun-Jee Oh   +10 more
doaj   +1 more source

Specular Microscopy Data of Cornea Bank Donors at Kartal Training and Research Hospital

Türk Oftalmoloji Dergisi, 2014
Objective: To evaluate the correlation between donor cornea endothelial cell morphology, epidemiological features of the donor and time of death in terms of necessity of specular microscopy (SM) in eye bank. Materials and Methods: SM data acquired from
Baki Kartal, Baran Kandemir, Berkay Akmaz, Süleyman Kuğu, Yusuf Özertürk, Turan Set, Hasan Altınkaynak, Sadullah Keleş   +7 more
doaj   +1 more source

Myocardial aging as a T-cell–mediated phenomenon [PDF]

, 2017
In recent years, the myocardium has been rediscovered under the lenses of immunology, and lymphocytes have been implicated in the pathogenesis of cardiomyopathies with different etiologies.
Abeßer, Marco, Beyersdorf, Niklas, Burkard, Matthias, Frantz, Stefan, Friedrich, Mike, Heinze, Katrin G., Hofmann, Ulrich, Jocelyne, Demengeot, Kerkau, Thomas, Nunes-Silva, Vânia, Peters, Laura, Pinnecker, Jürgen, Ramos, Gustavo Campos, Schuh, Kai, van den Berg, Anne, Weirather, Johannes   +15 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source