Imaging mass spectrometry approaches for the detection and localisation of drug compounds and small molecules in tissue [PDF]
A crucial and challenging aspect of the drug development process is the requirement to measure the distribution of a pharmaceutical compound and its metabolites in tissue.
Blatherwick, Eleanor Q.
core
iMetaMed, EarlyView.Integrated scRNA‐seq and spatial multiomics provide single‐cell and spatial insights into the neuroprotective effects of NGR1, a clinically validated bioactive compound from Panax notoginseng. NGR1 was associated with a shift in microglial transcriptional states away from ischemia‐associated pro‐inflammatory Adam8hi microglia and toward the protective ...
Qikun Zhao +10 more
wiley +1 more source
Evaluation of Cardiotoxic Effects of Anthracyclines by Tissue Doppler Imaging in Survivors of Childhood Cancer. [PDF]
Turk Arch Pediatr, 2021 Caliskan M +4 more
europepmc +1 more source
Klippel‐Trénaunay‐Weber Syndrome: Prenatal Diagnosis and Review of the Literature
Journal of Clinical Ultrasound, Volume 53, Issue 3, Page 535-546, March/April 2025.This meta‐analysis demonstrates the high diagnostic accuracy of SZ‐CEUS for differentiating between malignant and benign focal liver lesions, as well as for HCC from non‐HCC lesions. The study shows better performance for smaller lesions and those with a higher proportion of malignancy.
Giuliana Orlandi +13 more
wiley +1 more source
Journal of Clinical Ultrasound, Volume 53, Issue 3, Page 436-444, March/April 2025.The ultrasound detection rate of the palatine tonsils in children was good. There are characteristic ultrasonic image manifestations. Tonsil ultrasound image quality is affected by individual and local factors. ABSTRACT Objective To explore the ultrasonic image characteristics of palatine tonsils in healthy children and the factors affecting image ...
Ying Cao +5 more
wiley +1 more source
Journal of Clinical Ultrasound, EarlyView.Hip external rotation can cause compression of the quadratus femoris (QF) between the ischial tuberosity and lesser trochanter of the femur, resulting in pain in the buttock, hip, and groin which can radiate down the leg. Ultrasound imaging can demonstrate dynamic impingement of the QF, including symptom provocation.
Elaine Tyzack, Michelle Fenech
wiley +1 more source
STRAIN/STRAIN RATE ECHOCARDIOGRAPHY
Eurasian Journal of Medicine, 2019 The characterization of local myocardial deformation, for both local radial and longitudinal function, could be important in heart diseases. Strain and strain rate echocardiography derived tissue Doppler imaging is a new clinical approach to quantifying ...
Enbiya Aksakal
doaj
Echocardiography with tissue Doppler imaging may help in bedside differential diagnosis of pulmonary oedema in pregnancy: case report. [PDF]
Anaesthesiol Intensive Ther, 2022 Vassallo M, Bhakta P.
europepmc +1 more source
Contrast‐Enhanced Ultrasound in the Diagnosis of Parotid Gland Castleman Disease in a Child
Journal of Clinical Ultrasound, EarlyView.A 16‐year‐old girl with slowly progressive painless right parotid swelling. MRI demonstrated a T2‐hyperintense, markedly enhancing lesion suggestive of a vascular malformation. Fine‐needle aspiration yielded nonspecific lymphoid tissue. CEUS demonstrated rapid homogeneous enhancement of a hypervascular solid mass, raising suspicion for Castleman ...
Sruthilatha Sakthi Velavan +3 more
wiley +1 more source
Early right ventricular dysfunction after primary percutaneous coronary intervention in anterior versus isolated inferior myocardial infarction assessed by tissue Doppler imaging and speckle tracking echocardiography. [PDF]
Heart Fail Rev, 2023 Radwan HI +4 more
europepmc +1 more source