Results 161 to 170 of about 6,889,134 (415)

Tissue Engineering of Tendons [PDF]

open access: yes, 2008
Rupture of tendons due to either high load or laceration is a common injury, especially for the hand. Tendon disorders are traditionally treated by reducing inflammation, restoring flexibility, and, if necessary, performing surgical repair. It has been estimated that hand surgeons repair nearly one-third of a million digital flexor tendon injuries per ...
Pioletti, Dominique P.   +2 more
openaire   +3 more sources

Unraveling the metastasis‐preventing effect of miR‐200c in vitro and in vivo

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1029-1053, April 2025.
Advanced tumors and ineffective cancer treatments can lead to metastases in distant organs. The sole expression of microRNA 200c (miR‐200c) in breast cancer cells is shown to significantly reduce metastasis formation in xenograft mouse models. Various in vitro analyses revealed impeded migratory behavior, upon miR‐200c expression, as one prerequisite ...
Bianca Köhler   +12 more
wiley   +1 more source

Tissue engineering scaffold material of porous nanohydroxyapatite/polyamide 66

open access: yesInternational Journal of Nanomedicine, 2010
Qian Xu1, Hongyan Lu1, Jingchao Zhang1, Guoyu Lu2, Zhennan Deng2, Anchun Mo31State Key Laboratory of Oral Diseases, Sichuan University, Chengdu, 610041, P.R. China; 2Research Center for Nano-Biomaterials, Sichuan University, Chengdu, 610064, P.R.
Qian Xu   +3 more
doaj  

Hepatocyte Aggregates: Methods of Preparation in the Microgravity Simulating Bioreactor Use in Tissue Engineering [PDF]

open access: yesarXiv, 2008
Tissue Engineering concerns the three-dimensional cell growth so that bio-artificial tissues could be created and used for transplantation. The recently expressed concerns from the Tissue Engineering research community for a re-direction of the research activities necessitate the proposition of new methodologies. We propose a methodology that has to do
arxiv  

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Rapid prediction of organisation in engineered corneal, glial and fibroblast tissues using machine learning and biophysical models [PDF]

open access: yesarXiv
We present a machine learning approach for predicting the organisation of corneal, glial and fibroblast cells in 3D cultures used for tissue engineering. Our machine-learning-based method uses a powerful generative adversarial network architecture called pix2pix, which we train using results from biophysical contractile network dipole orientation ...
arxiv  

Recent Advancements in Regenerative Dentistry: A Review [PDF]

open access: yes, 2016
Although human mouth benefits from remarkable mechanical properties, it is very susceptible to traumatic damages, exposure to microbial attacks, and congenital maladies.
Amrollahi, Pouya   +3 more
core   +1 more source

Genomic landscape and preclinical models of angiosarcoma

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 965-983, April 2025.
Angiosarcomas are a rare and aggressive cancer with a poor prognosis for patients. The genomic landscape of angiosarcoma can be highly complex and heterogenous; however, recent studies have identified some common features especially within anatomic and molecular subgroups.
Annaleigh Benton   +3 more
wiley   +1 more source

Three-dimensional cell culture and tissue engineering in a T-CUP (tissue culture under perfusion) [PDF]

open access: yes, 2007
The aim of this study was to develop and validate a simple and compact bioreactor system for perfusion cell seeding and culture through 3-dimensional porous scaffolds.
Früh, Jennifer-Annika   +5 more
core  

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