Results 191 to 200 of about 6,889,134 (415)

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1517-1531, May 2025.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park   +6 more
wiley   +1 more source

Dermal fillers [PDF]

open access: yes, 2003
Tissue augmentation is a specialist area of bio-engineering which has been the subject of intrinsic research over the last twenty-five years, and represents a marriage of innovative pharmacology and chemical applications as diverse as reconstructive ...
Mallia, Alister
core  

Tissue engineering: Challenges and opportunities [PDF]

open access: hybrid, 2000
Mrunal S. Chapekar
openalex   +1 more source

SKA1 promotes oncogenic properties in oral dysplasia and oral squamous cell carcinoma, and augments resistance to radiotherapy

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1054-1074, April 2025.
The mitosis‐related gene SKA1 was among 629 genes consistently dysregulated in OSCC across nine public gene expression datasets. In OSCC cell lines, SKA1 promoted proliferation and migration, enhanced radioresistance, and reduced radiation‐induced senescence.
Alexander Michael Grandits   +7 more
wiley   +1 more source

New bioactive, degradable composite microspheres as tissue engineering substrates [PDF]

open access: bronze, 2000
Qingqing Qiu   +2 more
openalex   +1 more source

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1332-1346, May 2025.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang   +10 more
wiley   +1 more source

REGENERATIVE SIGNALS FOR INTESTINAL EPITHELIAL ORGANOID UNITS TRANSPLANTED ON BIODEGRADABLE POLYMER SCAFFOLDS FOR TISSUE ENGINEERING OF SMALL INTESTINE1,2

open access: bronze, 1999
Stephen S. Kim   +7 more
openalex   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

External loading determines specific ECM genes regulation [PDF]

open access: yes, 2006
Bio artificial matrices embedded with cells are simulated in bioreactors to facilitate ECM production. As cells attach, they develop forces, which are dependent on cell type and matrix stiffness.
Brown, R   +3 more
core  

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