Results 271 to 280 of about 6,889,134 (415)

Decellularization techniques: unveiling the blueprint for tracheal tissue engineering. [PDF]

open access: yesFront Bioeng Biotechnol
Gomes KT   +7 more
europepmc   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

3D bioprinting for biomedical devices and tissue engineering: A review of recent trends and advances

open access: yesBioactive Materials, 2018
Soroosh Derakhshanfar   +5 more
semanticscholar   +1 more source

The roles and applications of extracellular vesicles in cancer

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1287-1290, May 2025.
Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley   +1 more source

Development of biodegradable porous scaffolds for tissue engineering

open access: bronze, 2001
Guoping Chen   +2 more
openalex   +1 more source

Manufacturing and Characterization of 3‐D Hydroxyapatite Bone Tissue Engineering Scaffolds [PDF]

open access: green, 2002
Tien‐Min Gabriel Chu   +4 more
openalex   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

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