Results 21 to 30 of about 605,569 (200)

Introduction of ligated vessels promote the retention and regeneration of free fat: constructing a fat flap in tissue engineering chamber

Adipocyte, 2020
Background: Breast reconstruction with fat grafting has an unstable retention rate due to insufficient revascularization. Tissue Engineering Chamber (TEC) model can promote tissue regeneration in the chamber by introducing ligated vessels around the ...
Chen Lei, Beichen Cai, Xiaobin Chen, Zhiyong Huang, Biao Wang   +4 more
doaj   +1 more source

An Introduction to Tissue Engineering and Orthopedic Applications

Journal of Orthopedic and Spine Trauma, 2020
Nowadays, orthopedic-related pathologic conditions are considered as a growing concern. Also, the conventional treatments (grafting techniques) are not efficacious enough for the growing clinical needs.
Fatemeh Baghaie Nia, Fatemeh Khavari, Masoumeh Firouzi, Mohammad Hossein Nabian   +3 more
doaj   +1 more source

Segmental Additive Tissue Engineering

Scientific Reports, 2018
Segmental bone defects caused by trauma and disease represent a major clinical problem worldwide. Current treatment options are limited and often associated with poor outcomes and severe complications. Bone engineering is a promising alternative solution,
Martina Sladkova, Rawan Alawadhi, Rawan Jaragh Alhaddad, Asmaa Esmael, Shoug Alansari, Munerah Saad, Jenan Mulla Yousef, Lulwa Alqaoud, Giuseppe Maria de Peppo   +8 more
doaj   +1 more source

Biopolymers for Tissue Engineering [PDF]

Журнал Сибирского федерального университета: Серия Биология, 2014
A brief overview of the biopolymers used for cell and tissue engineering is presented. The results of research of matrices made from resorbable polyhydroxyalkanoates with different composition in fibroblast cell line culture are ...
Elena D. Nikolaeva
doaj  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

An ex vivo human cartilage repair model to evaluate the potency of a cartilage cell transplant

Journal of Translational Medicine, 2016
Background Cell-based therapies such as autologous chondrocyte implantation are promising therapeutic approaches to treat cartilage defects to prevent further cartilage degeneration.
Christoph Bartz, Miriam Meixner, Petra Giesemann, Giulietta Roël, Grit-Carsta Bulwin, Jeske J. Smink   +5 more
doaj   +1 more source

Engineering Human Beige Adipose Tissue

Frontiers in Bioengineering and Biotechnology, 2022
In this study, we described a method for generating functional, beige (thermogenic) adipose microtissues from human microvascular fragments (MVFs). The MVFs were isolated from adipose tissue acquired from adults over 50 years of age.
Maria A. Gonzalez Porras, Maria A. Gonzalez Porras, Katerina Stojkova, Francisca M. Acosta, Christopher R. Rathbone, Christopher R. Rathbone, Eric M. Brey, Eric M. Brey   +7 more
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

FEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii, Edoardo Andrea Cutolo, Daniele Montepietra, Claudia Battarra, Roberto Caferri, Stefano Capaldi, Zeno Guardini, Luca Dall'Osto, Roberto Bassi   +8 more
wiley   +1 more source