Results 41 to 50 of about 6,837,049 (299)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Tissue engineering in dentistry

Journal of Dentistry, 2014
of this review is to inform practitioners with the most updated information on tissue engineering and its potential applications in dentistry.The authors used "PUBMED" to find relevant literature written in English and published from the beginning of tissue engineering until today.
Abou Neel, Ensanya Ali, Chrzanowski, Wojciech, Salih, Vehid M., Kim, Hae-Won, Knowles, Jonathan C.   +4 more
openaire   +3 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Biomaterials for Neural Tissue Engineering

Frontiers in Nanotechnology, 2021
The therapy of neural nerve injuries that involve the disruption of axonal pathways or axonal tracts has taken a new dimension with the development of tissue engineering techniques.
Laura Rodríguez Doblado, Cristina Martínez-Ramos, Cristina Martínez-Ramos, Manuel Monleón Pradas, Manuel Monleón Pradas   +4 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Deformation-controlled load application in heart valve tissue engineering [PDF]

, 2008
In cardiovascular tissue engineering, mechanical stimulation of tissue-engineered constructs is known to improve tissue properties. During tissue culture, the mechanical properties of the tissue construct change.
Baaijens, FPT Frank, Baaijens, Frank P.T., Wijlaars, Marcel W., Marcel C. M. Rutten, Baaijens, F.P.T., Kortsmit, J Jeroen, Rutten, MCM Marcel, Frank P. T. Baaijens, Wijlaars, M.W., Rutten, Marcel C.M., Kortsmit, Jeroen, Rutten, M.C.M., Wijlaars, MW Marcel, Jeroen Kortsmit, Kortsmit, J., Marcel W. Wijlaars   +15 more
core   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Tissue Engineering in the Vasculature [PDF]

The Anatomical Record, 2013
ABSTRACTTissue engineering holds great promise to address complications and limitations encountered with the use of traditional prosthetic materials, such as thrombogenicity, infection, and future degeneration which represent the major morbidity and mortality after device implant surgery. The general concept of tissue engineering consists of three main
Yuji, Naito, Kevin, Rocco, Hirotsugu, Kurobe, Mark, Maxfield, Christopher, Breuer, Toshiharu, Shinoka   +5 more
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source