Results 51 to 60 of about 713,698 (308)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Advances in Tissue Engineering [PDF]
, 2004 The clinical goals of tissue engineering are to restore, repair, or replace damaged or lost tissues in the body. Significant progress has been made in recent years, which includes the use of cells or polymer scaffolds as well as combinations of cells and polymers for engineering three-dimensional tissue constructs.
Shulamit, Levenberg, Robert, Langer
openaire +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Deformation-controlled load application in heart valve tissue engineering [PDF]
, 2008 In cardiovascular tissue engineering, mechanical stimulation of tissue-engineered constructs is known to improve tissue properties. During tissue culture, the mechanical properties of the tissue construct change.
Baaijens, FPT Frank +15 more
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Tissue engineering: part 2 [Frontiers of biomedical engineering] [PDF]
, 2016 Educação Superior::Engenharias::Engenharia BiomédicaPresents a course about the basic concepts of biomedical engineering with the Professor of Chemical and Biomedical Engineering at Yale University, W. Mark Saltzman.
Saltzman, W. Mark
core +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Characterization of scaffolds for neural tissue engineering [PDF]
, 2023 With the advancement of tissue engineering techniques, the repair of nerve injuries has acquired a novel dimension. It is now appropriate to establish a scaffold that entirely mimics the biological and mechanical properties of real human tissue using ...
CESUR, SÜMEYYE, ULAĞ, SONGÜL
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Engineering Human Beige Adipose Tissue
Frontiers in Bioengineering and Biotechnology, 2022 In this study, we described a method for generating functional, beige (thermogenic) adipose microtissues from human microvascular fragments (MVFs). The MVFs were isolated from adipose tissue acquired from adults over 50 years of age.
Maria A. Gonzalez Porras +7 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source