Results 71 to 80 of about 7,368,901 (300)

Preclinical study of mouse pluripotent parthenogenetic embryonic stem cell derivatives for the construction of tissue-engineered skin equivalent

Stem Cell Research & Therapy, 2016
Background Embryonic stem cell (ESC) derivatives hold great promise for the construction of tissue-engineered skin equivalents (TESE). However, harvesting of ESCs destroys viable embryos and may lead to political and ethical concerns over their ...
Yang Rao, Jihong Cui, Lu Yin, Wei Liu, Wenguang Liu, Mei Sun, Xingrong Yan, Ling Wang, Fulin Chen   +8 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Characterization of scaffolds for neural tissue engineering

, 2023
With the advancement of tissue engineering techniques, the repair of nerve injuries has acquired a novel dimension. It is now appropriate to establish a scaffold that entirely mimics the biological and mechanical properties of real human tissue using ...
CESUR, SÜMEYYE, ULAĞ, SONGÜL
core  

Advancing osteochondral tissue engineering: bone morphogenetic protein, transforming growth factor, and fibroblast growth factor signaling drive ordered differentiation of periosteal cells resulting in stable cartilage and bone formation in vivo

Stem Cell Research & Therapy, 2018
Background Chondrogenic mesenchymal stem cells (MSCs) have not yet been used to address the clinical demands of large osteochondral joint surface defects.
L. F. Mendes, H. Katagiri, W. L. Tam, Y. C. Chai, L. Geris, S. J. Roberts, F. P. Luyten   +6 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Tissue engineering: part 2 [Frontiers of biomedical engineering]

, 2014
Educação Superior::Engenharias::Engenharia BiomédicaPresents a course about the basic concepts of biomedical engineering with the Professor of Chemical and Biomedical Engineering at Yale University, W. Mark Saltzman.
Saltzman, W. Mark
core  

Peripheral nerve tissue engineering

, 2021
Peripheral nerve injury is a frequent clinical problem and causes loss of motor and sensory functions for patients. Though some inherent regeneration capacity exists, this is often very limited in the cases of nerve tissue gaps.
Vijay Kumar Kuna, Paul J. Kingham, Kingham, Paul J.,, Kumar Kuna, Vijay,   +3 more
core   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Tissue engineering: part 2 [Frontiers of biomedical engineering]

, 2008
Educação Superior::Engenharias::Engenharia BiomédicaPresents a course about the basic concepts of biomedical engineering with the Professor of Chemical and Biomedical Engineering at Yale University, W. Mark Saltzman.
Saltzman, W. Mark
core  

Laser ice scaffolds modeling for tissue engineering [PDF]

, 2005
Tissue engineering is one of the most exciting and rapidly growing areas in biomedical engineering that offers vast potential for changing traditional approaches to meeting many pharmaceutics and critical health care needs.
Meglinski, I. V., Woodman, AC,, M Varejka, Turner, Anthony P. F., I V Meglinski, Woodman, Anthony C., S A Piletsky, A C Woodman, Meglinski, IV,, Turner, APF,, Piletsky, SA,, Varejka, M., Piletsky, Sergey A., A P F Turner, Varejka, M,   +14 more
core   +1 more source