Results 111 to 120 of about 166,368,995 (207)

Effects of benazepril on renal function and kidney expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in diabetic rats

open access: yesChinese Medical Journal, 2006
Excessive deposition of extracellular matrix (ECM) in the kidney is the hallmark of diabetic nephropathy. Increased matrix synthesis has been well documented but the effects of diabetes on degradative pathways, particularly in the in vivo setting. The renal protective effect of these pathways on matrix accumulation has not been fully elucidated.
Shu-zhen, Sun   +5 more
openaire   +2 more sources

Cell-based gene therapy modifies matrix remodeling after a myocardial infarction in tissue inhibitor of matrix metalloproteinase-3–deficient mice [PDF]

open access: yes, 2009
ObjectiveCell-based gene therapy can enhance the effects of cell transplantation by temporally and spatially regulating the release of the gene product. The purpose of this study was to evaluate transient matrix metalloproteinase inhibition by implanting
Seneviratne, Charit K.   +9 more
core   +1 more source

Release of tissue inhibitor of metalloproteinase-2 from alginate microcapsule encapsulating genetically engineered cells

open access: yes, 2013
Yeon Seong Kim,1,* Young-Il Jeong,2,* Shu-Guang Jin,2 Jian Pei,2 Min Wen,2 In-Young Kim,1 Kyung-Sub Moon,1 Tae-Young Jung,1 Hyang-Hwa Ryu2, Shin Jung1–3 1Department of Neurosurgery, 2Brain Tumor Research Laboratory, 3Chonnam National University ...
Jeong YI   +9 more
core  

Expressão das proteínas da matriz na discondroplasia da tíbia [PDF]

open access: yes, 2010
Doutoramento em BiologiaA discondroplasia da tíbia (TD) em aves consiste numa anomalia do esqueleto onde existe uma falha nos processos normais da ossificação endocondral.
Velada, Isabel de Jesus Pereira Godinho
core  

Serpin peptidase inhibitor, clade E, member 2 in physiology and pathology: recent advancements

open access: yesFrontiers in Molecular Biosciences
Serine protease inhibitors (serpins) are the most numerous and widespread multifunctional protease inhibitor superfamily and are expressed by all eukaryotes.
Shutong Wu   +7 more
doaj   +1 more source

Regulation of matrix-metalloproteinase 9 (MMP-9) in glomerular mesangial cells [PDF]

open access: yes, 2004
Remodeling of extracellular matrix (ECM) is an important physiologic feature of normal growth and development. In addition to this critical function in physiology many diseases have been associated with an imbalance of ECM synthesis and degradation.
Akool, El-Sayed
core  

Intracellular activation and processing of human disintegrin and metalloproteinase 19 (hADAM19) [PDF]

open access: yes, 2003
Kang T. Intracellular activation and processing of human disintegrin and metalloproteinase 19 (hADAM19). Bielefeld (Germany): Bielefeld University; 2003.Adamalysin 19 (a disintegrin and metalloproteinase 19, ADAM19, or meltrin [beta]) is a plasma ...
Kang, Tiebang
core  

The role of genetic factors in breast cancer aetiology [PDF]

open access: yes, 2010
Breast cancer is the most common cancer in women and is also the leading cause of cancermortality in women. There are several known risk factors for breast cancer including geneticfactors which account for at least 25% of the incidence of breast cancer ...
Hammond, Victoria Naomi
core  

Impact of the Synchronization of portulaca oleracea and Aerobic Training on Levels of MMP2 and MMP9 and TIMP1 in Diabetic Women Type II

open access: yesResearch in Molecular Medicine, 2014
Background: Diabetes has the most important role in development of tissue damage, and by affecting intercellular matrices, may lead to structural and functional changes that ultimately cause failure of related tissue or organ.
Parvin Farzanegi,
doaj  

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