Results 121 to 130 of about 118,809 (292)

Validating Homogeneity for a Novel 3-Dimensional Tissue Phantom Modeling System of the Human Maxilla. [PDF]

open access: yesProc SPIE Int Soc Opt Eng, 2023
Sourvanos D   +4 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Resonance frequency measurement to identify stiffness variations based on photoacoustic imaging

open access: yesBiophysics and Physicobiology
Linear assumption on the level of stiffness in a tissue shows a significant correlation with disease. Photoacoustic imaging techniques that are non-contact by design have been developed in this study to detect differences in phantom (soft tissue ...
Ananta Kusuma Yoga Pratama   +3 more
doaj   +1 more source

FPGA controlled artificial vascular system

open access: yesCurrent Directions in Biomedical Engineering, 2015
Monitoring the oxygen saturation of an unborn child is an invasive procedure, so far. Transabdominal fetal pulse oximetry is a promising method under research, used to estimate the oxygen saturation of a fetus noninvasively.
Laqua D.   +7 more
doaj   +1 more source

Microbubble dynamics and jetting near tissue-phantom biointerfaces. [PDF]

open access: yesBiomed Opt Express, 2022
Mur J   +3 more
europepmc   +1 more source

Effects of Blood Pressure and Intraocular Pressure on Ocular Arterial Blood Flow: Studies on in vitro Models [PDF]

open access: yes, 2018
Placed in 1st Place in the category of Cell Biology and Physiology, Denman ForumGlaucoma is the second leading cause of blindness around the world.
Kwok, Sunny
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Monte-Carlo simulation and tissue-phantom model for validation of ocular oximetry. [PDF]

open access: yesBiomed Opt Express, 2022
Akitegetse C   +5 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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