Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz +9 more
wiley +1 more source
Visual appearance of blood vessels: a phantom study. [PDF]
Wagner M +5 more
europepmc +1 more source
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht +53 more
wiley +1 more source
Accuracy of virtual non-contrast images from dual-energy integrating detector CT and photon-counting detector CT at high iodine concentrations. [PDF]
Grkovski R, Kulcsar Z, Winklhofer S.
europepmc +1 more source
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Engineering a High-Fidelity Neonatal Silicone Phantom: Development, Optimization, and User Evaluation of a 3D-Printed Vascular Access Model. [PDF]
Zoellner SD +3 more
europepmc +1 more source
Echo Intensity Correction Method for Ultrasound Computed Tomography in Musculoskeletal Imaging. [PDF]
Zeng J +9 more
europepmc +1 more source
Development and Phantom Validation of a Small-Form-Factor SWIR Emitter Probe for Hydration-Sensitive Spatial-Ratio Measurements in Gelatin-Intralipid Phantoms. [PDF]
Farouq G, Vyas D, Tofghi Zavareh A.
europepmc +1 more source
A MR Fingerprinting Development Kit for Quantitative 3D Brain Imaging. [PDF]
Boyacioglu R +11 more
europepmc +1 more source
Electromagnetic Performance Characterization and Circuit-Level Modeling of a Miniaturized Meander-Line Antenna for Implantable and Wearable RFID Applications. [PDF]
Ali W +4 more
europepmc +1 more source

