Results 111 to 120 of about 162,477 (300)

Clinical efficacy of low dose recombinant tissue-type plasminogen activator for the treatment of acute intermediate-risk pulmonary embolism [PDF]

open access: diamond, 2018
Lingyun Zhang   +10 more
openalex   +1 more source

Feasibility of Treating Eosinophilic Chronic Rhinosinusitis Using Short‐Chain Fatty Acids

open access: yesThe Laryngoscope, EarlyView.
Epithelial cell‐derived cytokines including thymic stromal lymphopoietin (TSLP) are important in the pathogenesis of chronic rhinosinusitis with nasal polyps. We demonstrate the inhibitory effect of TSLP production in airway epithelial cells and eosinophil survival by short‐chain fatty acids (SCFAs) as a potential new strategy to reduce nasal polyps ...
Rikako Gozawa   +12 more
wiley   +1 more source

A study of the interaction between Helicobacter pylori and components of the human fibrinolytic system

open access: yesBrazilian Journal of Medical and Biological Research, 2000
The interaction of plasminogen, tissue plasminogen activator (t-PA) and urokinase with a clinical strain of Helicobacter pylori was studied. Plasminogen bound to the surface of H. pylori cells in a concentration-dependent manner and could be activated to
A. Yarzábal   +5 more
doaj   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova   +3 more
wiley   +1 more source

A Global Transcriptomic Analysis Reveals Body Weight‐Specific Molecular Responses to Chronic Orange Juice Consumption in Healthy Individuals

open access: yesMolecular Nutrition &Food Research, EarlyView.
This study aimed to investigate the molecular pathways involved in the health benefits of chronic orange juice (OJ) consumption through global transcriptomic approach in peripheral blood mononuclear cells (PBMCs). Healthy volunteers consumed 500 mL of OJ daily for 60 days.
Layanne Nascimento Fraga   +6 more
wiley   +1 more source

Oncogenic H‐Ras Reprograms Madin‐Darby Canine Kidney (MDCK) Cell‐Derived Midbody Remnant Proteome Following Epithelial‐Mesenchymal Transition

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Epithelial‐mesenchymal transition (EMT) is a fundamental, dynamic cellular process involved in embryonic development, metastasis, organ fibrosis, and tissue regeneration. To define the molecular landscape of secreted midbody remnants (MBRs) to the EMT process, a proteome analysis of MBRs released from Madin–Darby canine kidney (MDCK) cells and
Adnan Shafiq   +6 more
wiley   +1 more source

First year of 24/7 Acute Stroke Unit. Part 2: outcome of stroke thrombolysis using telemedicine [PDF]

open access: yes, 2013
OBJECTIVE: To evaluate the safety and efficacy of intravenous recombinant tissue plasminogen activator (IV-rtPA) for acute ischaemic stroke through telemedicine consultation ...
Chang, C   +8 more
core  

Home - About - Disclaimer - Privacy