Results 301 to 310 of about 4,602,875 (389)
This study presents a custom‐made soft pneumatic device (SPD) that mimics complex mechanical forces and fluid flow to enhance in vitro cell differentiation. It shows that low mechanotransduction promotes MSC differentiation into osteoprogenitor cells, while high mechanotransduction causes structural disruptions and cell detachment, providing new ...
Gwang‐Bum Im+9 more
wiley +1 more source
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo+11 more
wiley +1 more source
Salt‐Compact Albumin as a New Pure Protein‐based Biomaterials: From Design to In Vivo Studies
A new class of materials built entirely of native albumin protein is designed using a simple protocol based on salt‐assisted compaction, breaking with current crosslinking strategies. This green process leads, surprisingly, to water‐insoluble handable materials with high preservation of their native protein structures and Young's modulus close to that ...
Eya Aloui+19 more
wiley +1 more source
Dorsolateral fibromuscular tissue preservation during artificial urinary sphincter cuff placement is associated with low infection and erosion rates. [PDF]
Cheung F+5 more
europepmc +1 more source
Glepaglutide (GL), a GLP‐2 analog with an extended half‐life (50 h), is currently undergoing clinical trials for patients with short bowel syndrome. GL requires subcutaneous injection, which poses challenges for potential patient compliance. To address this challenge, we loaded GL into a rectal foam formulation using CO2 as a permeation enhancer to ...
Wunan Zhang+9 more
wiley +1 more source
This study presents a novel implantable drug delivery systemwith a biodegradable poly(caprolactone) membrane and compressed drug core forsustained release. These implantable devices deliver risperidone in vitro for 170 days and in vivo for 49 days in rats, showing promise for chronic conditions like schizophrenia.
Linlin Li+9 more
wiley +1 more source
Comparison of superoxide dismutase, allopurinol, coenzyme Q10, and glutathione for the prevention of warm ischemic injury [PDF]
Cho, WH+5 more
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