Results 131 to 140 of about 702,874 (310)

VIVID: A qPCR‐Based Platform for Sensitive and Quantitative In Vivo Tracking of Extracellular Vesicles

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces VIVID (Vesicle In Vivo Identification using DNA), a qPCR‐based platform that tracks PCR‐amplifiable DNA tags loaded in the EVs for accurate and quantifiable EV biodistribution in vivo. ABSTRACT Extracellular vesicles (EVs) represent promising carriers for nucleic acid therapeutics, offering advantages over synthetic nanoparticles ...
Oscar Boyadjian   +5 more
wiley   +1 more source

Mechanoregulatory Effects of Cell‐Scale Microwells on Epithelial Cell Phenotype

open access: yesAdvanced Functional Materials, EarlyView.
In small polycaprolactone microwells, A549 epithelial cells span well edges, in contrast to cells growing on flat substrates. Focal adhesion sites (yellow) concentrate at topographic boundaries, while cytoskeletal tension (magenta stress fibers) is transmitted to the nucleus (blue), reducing nuclear sphericity.
Ruiwen He   +10 more
wiley   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

open access: yesAdvanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim   +6 more
wiley   +1 more source

Trxr-Mimetic Se/S-Carbon Dots Promote Infected Wound Healing

open access: yesInternational Dental Journal
Aim or purpose: To construct selenium-sulfur doped carbon dots (SE/S CDs) with the biomimetic activity of thioredoxin reductase, and to explore their effect on the healing of infected wounds.
Mengmeng Cao   +3 more
doaj   +1 more source

From Clinic to Computation: Multiscale Bioengineering Strategies for Durable Biological Aortic Valve Replacements

open access: yesAdvanced Functional Materials, EarlyView.
Bioprosthetic aortic valves have revolutionized the treatment of aortic stenosis, but their durability is limited by structural valve deterioration (SVD). This review focuses on the pericardial tissue at the heart of these valves, examining how its mechanical properties and calcification drive fatigue and failure.
Gabriele Greco   +7 more
wiley   +1 more source

Matrix‐Rigidity Cooperates With Biochemical Cues in M2 Macrophage Activation Through Increased Nuclear Deformation and Chromatin Accessibility

open access: yesAdvanced Science
Macrophages encounter a myriad of biochemical and mechanical stimuli across various tissues and pathological contexts. Notably, matrix rigidity has emerged as a pivotal regulator of macrophage activation through mechanotransduction.
Seung Jae Shin   +11 more
doaj   +1 more source

In Situ 3D Bioprinting: Impact of Cross‐Linking on the Adhesive Properties of Hydrogels

open access: yesAdvanced Functional Materials, EarlyView.
In situ 3D bioprinting enables the direct deposition of cell‐laden, adhesive biomaterials for on‐site tissue regeneration. This review provides a comprehensive overview of how cross‐linking influences the bioadhesive properties of hydrogels used in 3D bioprinting, highlighting cross‐linking triggers, bioadhesion mechanisms, polymer interpenetration ...
Odile Romero Fernandez   +4 more
wiley   +1 more source

Additive Manufacturing of NiTi Shape Memory Alloys for Elastocaloric Applications: A Review

open access: yesAdvanced Functional Materials, EarlyView.
Additive manufacturing enables complex NiTi architectures that overcome key limitations in elastocaloric refrigeration, including poor heat transfer and high mechanical work input. This review surveys recent advances in LPBF‐ and DED‐fabricated NiTi shape memory alloys for elastocaloric applications, highlighting process–structure–performance ...
Ignatius Andre Setiawan   +7 more
wiley   +1 more source

Plant regeneration from leaf-derived callus cultures of Primrose (Primula vulgaris) [PDF]

open access: yes, 2016
Efficient micropropagation of Primula species is important both for fundamental scientific studies and commercial applications. Primula vulgaris, along with other Primulaceae species, exhibits floral heteromorphy with two distinct forms of hermaphroditic
Gilmartin, Philip   +4 more
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