Results 41 to 50 of about 127,780 (264)

Biomimicking trilayer scaffolds with controlled estradiol release for uterine tissue regeneration

open access: yesExploration
Scaffold‐based tissue engineering provides an efficient approach for repairing uterine tissue defects and restoring fertility. In the current study, a novel trilayer tissue engineering scaffold with high similarity to the uterine tissue in structure was ...
Shangsi Chen   +4 more
doaj   +1 more source

Polyfunctional Scaffolds for Tissue Engineering

open access: yesJournal of Biomechanical Science and Engineering, 2006
Three-dimensional porous scaffolds play an important role for tissue engineering. The recent developments of porous scaffolds and their preparation methods, especially those developed by our group, are summarized in this review.
Tetsuya TATEISHI   +2 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Chitosan/hydroxyapatite scaffolds for tissue engineering manufacturing method effect comparison

open access: yesRevista Facultad de Ingeniería Universidad de Antioquia, 2015
The regeneration of bone is one of the main challenges of modern medicine because many diseases including trauma and tumor can cause bone defects.
Diana Marcela Escobar-Sierra   +2 more
doaj   +1 more source

3D printing of bone tissue engineering scaffolds

open access: yesBioactive Materials, 2020
Tissue engineering is promising in realizing successful treatments of human body tissue loss that current methods cannot treat well or achieve satisfactory clinical outcomes.
Chong Wang   +11 more
doaj   +1 more source

Chitin Scaffolds in Tissue Engineering [PDF]

open access: yesInternational Journal of Molecular Sciences, 2011
Tissue engineering/regeneration is based on the hypothesis that healthy stem/progenitor cells either recruited or delivered to an injured site, can eventually regenerate lost or damaged tissue. Most of the researchers working in tissue engineering and regenerative technology attempt to create tissue replacements by culturing cells onto synthetic porous
Rangasamy Jayakumar   +5 more
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Photothermal nanomaterials-based scaffolds for tissue regeneration and cancer therapy

open access: yesMedicine in Novel Technology and Devices
Recently, photothermal therapy (PTT) has been considered a promising method for cancer treatment with fewer serious side effects compared to conventional radiation, chemotherapy and surgical resection.
Kuldeep Rajpoot
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

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