Results 51 to 60 of about 1,964,988 (291)

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Biomimicking trilayer scaffolds with controlled estradiol release for uterine tissue regeneration

open access: yesExploration
Scaffold‐based tissue engineering provides an efficient approach for repairing uterine tissue defects and restoring fertility. In the current study, a novel trilayer tissue engineering scaffold with high similarity to the uterine tissue in structure was ...
Shangsi Chen   +4 more
doaj   +1 more source

Nanotechnology Biomimetic Cartilage Regenerative Scaffolds

open access: yesArchives of Plastic Surgery, 2014
Cartilage has a limited regenerative capacity. Faced with the clinical challenge of reconstruction of cartilage defects, the field of cartilage engineering has evolved. This article reviews current concepts and strategies in cartilage engineering with an
Erh-Hsuin Lim   +2 more
doaj   +1 more source

Plant-Based Scaffolds in Tissue Engineering

open access: yesACS Biomaterials Science & Engineering, 2021
A wide range of platforms has been developed for 3D culture of cells in vitro to aggregate and align cells to resemble in vivo conditions in order to enhance communication between cells and promote differentiation. The cellulose skeleton of plant tissue can serve as an attainable scaffold for mammalian cells after decellularization, which is ...
Asu Ceren Bilirgen   +5 more
openaire   +3 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Engineering contractile myocardial tissue using extracellular matrix scaffolds [PDF]

open access: yes, 2013
There is currently an overwhelming need for functional replacement of diseased or damaged cardiac tissue. Biologic based scaffolds are an attractive tissue engineering approach to cardiac repair because they avoid sensitization associated with homograft ...
Remlinger, Nathaniel
core  

In situ surface functionalisation of scaffolds using block copolymer self-assembly [PDF]

open access: yes, 2013
Understanding human mesenchymal stem cell (hMSC) adhesion and differentiation in three-dimensional matrices in vitro is important for potential regenerative medicine and stem cell therapies.
Viswanathan, Priyalakshmi
core   +5 more sources

3D printing of bone tissue engineering scaffolds

open access: yesBioactive Materials, 2020
Tissue engineering is promising in realizing successful treatments of human body tissue loss that current methods cannot treat well or achieve satisfactory clinical outcomes.
Chong Wang   +11 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Three-dimensional cell culture and tissue engineering in a T-CUP (tissue culture under perfusion) [PDF]

open access: yes, 2007
The aim of this study was to develop and validate a simple and compact bioreactor system for perfusion cell seeding and culture through 3-dimensional porous scaffolds.
Früh, Jennifer-Annika   +5 more
core  

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