New emerging approaches in tissue engineering include incorporation of metal ions involved in various metabolic processes, such as Cu, Zn, Si into bioceramic scaffolds for enhanced cell growth and differentiation of specific cell types.
Kontonasaki E. +10 more
doaj +1 more source
Introduction to the Special Issue on Stem Cell and Biologic Scaffold Engineering
Tissue engineering and regenerative medicine is a rapidly evolving research field that effectively combines stem cells and biologic scaffolds in order to replace damaged tissues. Biologic scaffolds can be produced through the removal of resident cellular
Panagiotis Mallis +2 more
doaj +1 more source
Carboxyl-modified single-wall carbon nanotubes improve bone tissue formation in vitro and repair in an in vivo rat model. [PDF]
The clinical management of bone defects caused by trauma or nonunion fractures remains a challenge in orthopedic practice due to the poor integration and biocompatibility properties of the scaffold or implant material. In the current work, the osteogenic
Barrientos-Durán, Antonio +5 more
core +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Injectable Scaffolds for Adipose Tissue Reconstruction
Autologous fat grafting is the main surgical technique for soft tissue reconstruction. However, its clinical use with more extended volumes is limited by repeated procedures due to the little possibility of banking tissue, donor-site morbidity and ...
Valeria Pruzzo +5 more
doaj +1 more source
SLS Fabrication of Highly Porous Model Including Fine Flow Channel Network Aiming at Regeneration of Highly Metabolic Organs [PDF]
Fabrication of very porous scaffold for regeneration of highly metabolic organs is reported. Polycaprolactone (PCL) powder was mixed with fine salt grains as filler and SLS processed to develop a model including fine flow channel network.
Huang, Hongyun +3 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Carbon nanomaterials‐based electrically conductive scaffolds for tissue engineering applications
In tissue engineering, the pivotal role of scaffolds is underscored, serving as key elements to emulate the native extracellular matrix. These scaffolds must provide structural integrity and support and supply electrical, mechanical, and chemical cues ...
Genevieve Abd +8 more
doaj +1 more source
Nanofibers serve as widely employed tissue engineering scaffolds in diverse biomedical applications. When implanted in vivo, it is crucial for tissue engineering scaffolds to be visualizable, enabling the monitoring of their shape, position, and ...
Congyi Yang +10 more
doaj +1 more source
Innovative approach for the in vitro research on biomedical scaffolds designed and customized with CAD-CAM technology [PDF]
Studies on biomaterials involve assays aimed to assess the interactions between the biomaterial and the cells seeded on its surface. However, the morphology of biomaterials is heterogeneous and it could be tricky to standardize the results among ...
Apicella, Davide +11 more
core +1 more source

