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Nidogen‐1 Mitigates Ischemia and Promotes Tissue Survival and Regeneration [PDF]

open access: yesAdvanced Science, 2021
Ischemia impacts multiple organ systems and is the major cause of morbidity and mortality in the developed world. Ischemia disrupts tissue homeostasis, driving cell death, and damages tissue structure integrity.
Aline Zbinden   +20 more
doaj   +3 more sources

Bevacizumab effect on viability of free groin flaps in rats [PDF]

open access: yesRevista Brasileira de Cirurgia Plástica, 2023
Introduction: Bevacizumab is among the most frequently used drugs in cancer treatment. There is evidence that some anti-angiogenic drugs reduce flap survival, but it is unclear whether this applies to Bevacizumab.
João Mamede   +3 more
doaj   +1 more source

Pancreatic cancer patient survival correlates with DNA methylation of pancreas development genes. [PDF]

open access: yes, 2015
DNA methylation is an epigenetic mark associated with regulation of transcription and genome structure. These markers have been investigated in a variety of cancer settings for their utility in differentiating normal tissue from tumor tissue.
Dawson, David W   +4 more
core   +18 more sources

Actual long-term survival after resection of stage III soft tissue sarcoma

open access: yesBMC Cancer, 2021
Background Actuarial survival based on the Kaplan–Meier method can overestimate actual long-term survival, especially among those with factors of poor prognosis.
Do Weon Lee, Han-Soo Kim, Ilkyu Han
doaj   +1 more source

A novel deep learning-based algorithm combining histopathological features with tissue areas to predict colorectal cancer survival from whole-slide images

open access: yesJournal of Translational Medicine, 2023
Background Many methodologies for selecting histopathological images, such as sample image patches or segment histology from regions of interest (ROIs) or whole-slide images (WSIs), have been utilized to develop survival models.
Yan-Jun Li   +4 more
doaj   +1 more source

Adipose Tissue Distribution Predicts Survival in Amyotrophic Lateral Sclerosis. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND:amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that leads to death within a few years after diagnosis. Malnutrition and weight loss are frequent and are indexes of poor prognosis.
Eva Lindauer   +5 more
doaj   +1 more source

Expression of IL4Rα and IL13Rα1 are associated with poor prognosis of soft-tissue sarcoma of the extremities, superficial trunk, and retroperitoneum

open access: yesDiagnostic Pathology, 2021
Background IL4Rα and IL13Rα1 are constituents of the type II IL4 receptor. Recently, IL4Rα and IL13Rα1 were reported to have roles in cancer progression and suggested as potential prognostic markers.
Kyoung Min Kim   +9 more
doaj   +1 more source

Histological Evaluation of Resected Tissue as a Predictor of Survival in Horses with Strangulating Small Intestinal Disease

open access: yesAnimals, 2023
Strangulating small intestinal disease (SSID) in horses carries a poor prognosis for survival, especially following resection of ischaemic tissue. The margins of a resection are principally based on visual appraisal of the intestine during surgery.
David Bardell   +3 more
doaj   +1 more source

Insurance impacts survival for children, adolescents, and young adults with bone and soft tissue sarcomas. [PDF]

open access: yes, 2020
BackgroundWhile racial/ethnic survival disparities have been described in pediatric oncology, the impact of income has not been extensively explored. We analyzed how public insurance influences 5-year overall survival (OS) in young patients with sarcomas.
Goldsby, Robert E   +5 more
core   +1 more source

Expression of Matrix Metalloproteinase-2/9 and Tissue Inhibitor of Metalloproteinase-1/2 as Predictive Factors in Oropharyngeal Squamous Cell Carcinoma [PDF]

open access: yesIranian Journal of Otorhinolaryngology, 2019
Introduction: Metalloproteinases and their tissue inhibitors play an important role in the metastases formation. A multistage process of carcinogenesis requires the involvement of numerous enzymes and compounds that facilitate the expansion of tumor ...
Pawel Burduk   +4 more
doaj   +1 more source

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