Results 41 to 50 of about 8,112,821 (345)

Expression of immune-related guanosine triphosphatase M in colorectal cancer and its association with clinicopathological features and prognosis [PDF]

精准医学杂志
Objective To investigate the expression characteristics of immune-related guanosine triphosphatase M (IRGM) in colorectal cancer (CRC) tissue and its association with clinicopathological features and prognosis.
LI Na, RAN Wenwen, ZHAO Han, XING Xiaoming
doaj   +1 more source

Human prostate sphere-forming cells represent a subset of basal epithelial cells capable of glandular regeneration in vivo. [PDF]

, 2009
BackgroundProstate stem/progenitor cells function in glandular development and maintenance. They may be targets for tumor initiation, so characterization of these cells may have therapeutic implications.
Garraway, Isla P, Goldstein, Andrew S, Hahm, Scott A, Haider, Maahum, Head, Christian S, Perner, Sven, Reiter, Robert E, Rubin, Mark A, Sun, Wenyi, Tran, Chau P, Witte, Owen N, Zhang, Bao   +11 more
core   +1 more source

Superficial soft tissue sarcomas: 10‑year survival outcomes

Oncology Letters, 2023
Cutaneous sarcomas comprise a broad group of rare, heterogeneous mesenchymal tumours. The present report describes a single centre experience regarding the management and the outcomes of patients with superficial soft tissue sarcomas (SSTS). Key prognostic factors in predicting overall survival (OS) and local relapse-free survival were determined. Data
Tolia, Maria, Gkantaifi, Areti, Hayward, Larry, Gupta, Girish, Kyriazoglou, Anastasios, Mauri, Davide, Nixon, Ioanna   +6 more
openaire   +3 more sources

Altered brain energetics induces mitochondrial fission arrest in Alzheimer's Disease. [PDF]

, 2016
Altered brain metabolism is associated with progression of Alzheimer's Disease (AD). Mitochondria respond to bioenergetic changes by continuous fission and fusion.
Bachmeier, Benjamin V, Christensen, Trace A, Diaz Brinton, Roberta, Gateno, Benjamin, Gylys, Karen H, Itoh, Kie, Parisi, Joseph E, Patterson, Emily R, Poon, Wayne W, Salisbury, Jeffrey L, Schroeder, Andreas, Sesaki, Hiromi, Trushin, Sergey, Trushina, Eugenia, Yao, Jia, Zhang, Liang   +15 more
core   +1 more source

Feature-Guided Deep Radiomics for Glioblastoma Patient Survival Prediction

Frontiers in Neuroscience, 2019
Glioblastoma is recognized as World Health Organization (WHO) grade IV glioma with an aggressive growth pattern. The current clinical practice in diagnosis and prognosis of Glioblastoma using MRI involves multiple steps including manual tumor sizing ...
Zeina A. Shboul, Mahbubul Alam, Lasitha Vidyaratne, Linmin Pei, Mohamed I. Elbakary, Khan M. Iftekharuddin   +5 more
doaj   +1 more source

Pan-urologic cancer genomic subtypes that transcend tissue of origin [PDF]

, 2017
Urologic cancers include cancers of the bladder, kidney, prostate, and testes, with common molecular features spanning different types. Here, we show that 1954 urologic cancers can be classified into nine major genomic subtypes, on the basis of ...
Bossé, Dominick, Chen, Fengju, Choueiri, Toni K, Creighton, Chad J, Gibbons, Don L, Hakimi, A. Ari, Hsieh, James J, Ittmann, Michael, Lalani, Aly-Khan A, Zhang, Yiqun   +9 more
core   +2 more sources

IMPACTS OF TISSUE-TYPE PLASMINOGEN ACTIVATOR (TPA) ON NEURONAL SURVIVAL

Frontiers in Cellular Neuroscience, 2015
Tissue-type plasminogen activator (tPA) a serine protease is constituted of five functional domains through which it interacts with different substrates, binding proteins and receptors.
Arnaud eChevilley, Flavie eLesept, Sophie eLenoir, Carine eAli, Jérôme eParcq, Denis eVivien   +5 more
doaj   +1 more source

Tissue-resident FOLR2+ macrophages associate with CD8+ T cell infiltration in human breast cancer

Cell, 2022
Macrophage infiltration is a hallmark of solid cancers, and overall macrophage infiltration correlates with lower patient survival and resistance to therapy.
Rodrigo Nalio Ramos, Y. Missolo-Koussou, Yohan Gerber-Ferder, Christian P. Bromley, Mattia Bugatti, N. Núñez, J. Tosello Boari, W. Richer, Laurie Menger, Jordan Denizeau, C. Sedlik, P. Caudana, Fiorella Kotsias, L. L. Niborski, S. Viel, Mylène Bohec, S. Lameiras, S. Baulande, Laëtitia Lesage, A. Nicolas, D. Meseure, A. Vincent‐Salomon, F. Reyal, C. Dutertre, F. Ginhoux, L. Vimeux, E. Donnadieu, Bénédicte Buttard, J. Galon, S. Zelenay, W. Vermi, P. Guermonprez, E. Piaggio, J. Helft   +33 more
semanticscholar   +1 more source

The microbiome types of colorectal tissue are potentially associated with the prognosis of patients with colorectal cancer

Frontiers in Microbiology, 2023
As the second leading cause of cancer worldwide, colorectal cancer (CRC) is associated with a poor prognosis. Although recent studies have explored prognostic markers in patients with CRC, whether tissue microbes carry prognostic information remains ...
Yixin Xu, Jing Zhao, Yu Ma, Jia Liu, Yingying Cui, Yuqing Yuan, Chenxi Xiang, Dongshen Ma, Hui Liu, Hui Liu   +9 more
doaj   +1 more source

Nutritional and Behavioral Intervention for Long‐Term Childhood Acute Leukemia Survivors With Metabolic Syndrome

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Metabolic syndrome (MetS) is a common complication in survivors of childhood acute lymphoblastic and myeloid leukemia (AL), and a major risk factor for premature cardiovascular disease, type‐2‐diabetes, and metabolic dysfunction‐associated steatotic liver disease (MASLD).
Visentin Sandrine, Béliard Sophie, Renard Cécile, Caussy Cyrielle, Hamidou Zeinab, Romano David, Gacem Mélanie, Petit Arnaud, Saultier Paul, Borentain Patrick, Michel Gérard   +10 more
wiley   +1 more source