Results 161 to 170 of about 2,522,129 (303)

Thymosin Alpha‐1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis

Advanced Science, EarlyView.
In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang, Shisi Wang, Liubin Zhang, Mengyan Hu, Xiaotao Su, Yuxin Liu, Qin Qin, Haotong Yi, Liling Yuan, Wei Cai, Lei Wei, Zhengqi Lu   +11 more
wiley   +1 more source

P31-A150 SARS-CoV-2 real time polymerase chain reaction testing of corneas from post-mortem SARS-CoV-2 positive donors

BMJ Open Ophthalmology, 2023
Marina Roncevic Krajina, Ivana Vidovic, Branka Golubic Cepulic, Ivana Juric, Elizabeta Zaplatic, Dolores Bukulin, Tomislav Popović, Ana Budimir   +7 more
doaj   +1 more source

Testicular tissue transplantation: from animal models to clinical application. [PDF]

Hum Reprod Open
De Beer E, Goossens E.
europepmc   +1 more source

A Systematic Review of Ovarian Tissue Transplantation Outcomes by Ovarian Tissue Processing Size for Cryopreservation. [PDF]

Front Endocrinol (Lausanne), 2022
Diaz AA, Kubo H, Handa N, Hanna M, Laronda MM.   +4 more
europepmc   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

Hydrogen-generating nanomodulators for metabolic repair and functional recovery in ovarian tissue transplantation. [PDF]

J Nanobiotechnology
Jiang M, Liu J, Zhao Y, Bai X, Yan H, Zeng Q, Wang L, Liao Y, Xiong D, Xie H, Luan Z, Yu L, He L, Zhou Z, Zhang G, Miao YB, Liu W.   +16 more
europepmc   +1 more source

Adult spinal cord tissue transplantation combined with local tacrolimus sustained-release collagen hydrogel promotes complete spinal cord injury repair. [PDF]

Cell Prolif, 2023
Zhao X, Gu R, Zhao Y, Wei F, Gao X, Zhuang Y, Xiao Z, Shen H, Dai J.   +8 more
europepmc   +1 more source

Breast Cancer Tissue Bank Search Tool

The Research Query page is a component of the Breast Cancer Tissue Bank website. It shows the numbers of consented patients, and the numbers of available samples.

core  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

One-stage scalp composite tissue transplantation for the correction of pinched nose deformity in Asian patients undergoing revision rhinoplasty. [PDF]

Sci Rep
Xu MQ, He JM, Sun YX, Yu BF, Dai CC.
europepmc   +1 more source