Results 181 to 190 of about 421,672 (303)

Applying plastic surgery principles to ovarian tissue transplantation. [PDF]

Gland Surg, 2021
Shen AY, Rozen WM, Polyakov A, Stern K, Rozen G.   +4 more
europepmc   +1 more source

Disruption of the SNRPF–DDX24–E2F4 Feedback Loop Uncouples Splicing and Transcriptional Regulation to Suppress Ovarian Cancer Progression

Advanced Science, EarlyView.
This study identifies SNRPF as a critical oncogenic driver in ovarian cancer. By regulating a self‐sustaining SNRPF–DDX24–E2F4 feedback loop through intron retention and nonsense‐mediated decay, SNRPF couples RNA splicing with transcriptional regulation to promote tumor progression.
Yingwei Li, Zhongshao Chen, Qianqian Gao, Yuehan Gao, Ning Yang   +4 more
wiley   +1 more source

Injectable Cell-based Tissue Engineered Bone Formulations

, 2010
PhDCurrent golden standard therapy for bone repair and regeneration involves the use of auto grafts. Nevertheless, there are many drawbacks associated with auto grafts including donor site morbidity, requirement for an invasive surgery, post-operative
Ahmadi, Raheleh
core  

Developing Mouse Models for Ovarian Tissue Transplantation and Xenotransplantation: A Review. [PDF]

Med Sci Monit
Liu FX, Lin Z, Huang KL.
europepmc   +1 more source

Epigenetic Silencing of RFX7 Defines a Transcriptional Axis Linking Lactate Metabolism to Immune Checkpoint Therapy in Glioblastoma

Advanced Science, EarlyView.
Glioblastoma (GBM) exhibits RFX7 silencing via promoter hypermethylation, which downregulates PIK3IP1 to activate PI3K/AKT signaling, increase lactate accumulation, and enhance histone H4K12 lactylation. This lactylation upregulates PD‐L1/CSF1 expression and drives the immunosuppressive microenvironment formation.
Liying Han, Jinpeng Zhou, Gang Zhu, Fan Chen, Leiyang Li, Wenxing Cui, Fang Sun, Tian Feng, Yue Zhang, Qiang Wang, Shuoyao Ma, Chengxuan Guo, Ziwen Zhang, Kai Wang, Jiahui Wang, Liangbo Wang, Wencong Li, Chenyi Yuan, Haixiao Liu, Liang Wang, Yan Qu   +20 more
wiley   +1 more source

Neural tissue xenotransplantation What Is Needed Prior to Clinical Trials in Parkinson’s Disease?

, 2000
Embryonic allografted human tissue in patients with Parkinson's disease has been shown to survive and ameliorate many of the symptoms of this disease. Despite this success, the practical problems of using this tissue coupled to the ethical restrictions ...
Neural Tissue Xenografting Project, Lund University.   +1 more
core  

Brown adipose tissue transplantation ameliorates hindlimb ischemic damage in diabetic mice. [PDF]

Sci Rep
Lu T, Liu A, Li C, Li Y, Yang B, Liu Q, Jiang H.   +6 more
europepmc   +1 more source

Reconstruction of the trachea and carina: Surgical reconstruction, autologous tissue transplantation, allograft transplantation, and bioengineering. [PDF]

Thorac Cancer, 2022
Ren J, Xu Y, Zhiyi G, Ren T, Ren J, Wang K, Luo Y, Zhu M, Tan Q.   +8 more
europepmc   +1 more source

Optimized Ex Vivo Human Liver Slice Culture Maintains Extended Viability and Function for Hepatotoxicity Testing

Advanced Science, EarlyView.
An optimized ex vivo human liver slice culture system preserves tissue architecture, hepatocyte function, and immune‐stromal complexity for at least five days. By refining slice thickness, oxygenation, air‐liquid interface, and extracellular matrix support, the platform enables human‐relevant hepatotoxicity testing and mechanistic studies, offering a ...
Huiche Feng, Cinzia Esposito, Andrej Benjak, Matthias S. Matter, Miriam Cieri, Camilla De Carlo, Philipp Sedlaczek, Fabian Haak, Mattia Marinucci, Gabriel Fridolin Hess, Otto Kollmar, Mairene Coto‐Llerena, Luca Di Tommaso, Visar Vela, Lukas Bubendorf, Luigi M. Terracciano, Charlotte K. Y. Ng, Salvatore Piscuoglio   +17 more
wiley   +1 more source

Enhancement of angiogenesis and follicular survival using growth factors during ovarian tissue transplantation: a systematic review. [PDF]

Arch Gynecol Obstet
Zhang L, Zhang M, Jiang X, Wang M, Shu H, Wang G, Li P, Wu M, Zhang W, He L.   +9 more
europepmc   +1 more source