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Titer regulation in arthropod-Wolbachia symbioses [PDF]

open access: yesFEMS Microbiology Letters, 2019
ABSTRACT Symbiosis between intracellular bacteria (endosymbionts) and animals are widespread. The alphaproteobacterium Wolbachia pipientis is known to maintain a variety of symbiotic associations, ranging from mutualism to parasitism, with a wide range of invertebrates.
Elves Heleno Duarte   +2 more
openaire   +5 more sources

Improved Zika virus plaque assay using Vero/TMPRSS2 cell line [PDF]

open access: yesMicrobiology Spectrum
Plaque assay is the gold standard for the quantification of viable cytopathic viruses like Zika virus (ZIKV). Some strains of ZIKV produce plaques that are very difficult to accurately visualize and count on the commonly used Vero cell line.
Olukunle O. Oluwasemowo   +3 more
doaj   +2 more sources

The impact of host diet on Wolbachia titer in Drosophila. [PDF]

open access: yesPLoS Pathogens, 2015
While a number of studies have identified host factors that influence endosymbiont titer, little is known concerning environmental influences on titer. Here we examined nutrient impact on maternally transmitted Wolbachia endosymbionts in Drosophila.
Laura R Serbus   +6 more
doaj   +2 more sources

Differing Transcriptomic Responses in High Titer versus Low Titer Aedes aegypti Mosquitoes after Oral Infection with Sindbis Virus [PDF]

open access: yesViruses
Oral infection of mosquitoes by arboviruses often results in a large degree of variation in the amount of infectious virus between individual mosquitoes, even when the mosquitoes are from inbred laboratory strains.
Peter Hodoameda   +3 more
doaj   +2 more sources

Prospects of bacteriophage collections in disinfectant applications [PDF]

open access: yesVeterinary World, 2022
Background and Aim: The search and development of disinfectants is promising worldwide. However, there are currently no international regulations governing the testing and registration of germicidal agents. Moreover, the number of safety requirements for
Samat Serikovich Issabekov   +4 more
doaj   +1 more source

Prevention of severe COVID-19 in the elderly by early high-titer plasma therapy

open access: yesNew England Journal of Medicine, 2021
Background Therapies to interrupt progression of early COVID-19 remain elusive. Among them, convalescent plasma in hospitalized patients was unsuccessful, perhaps because antibody should be administered earlier.
R. Libster   +55 more
semanticscholar   +1 more source

Evaluation of a New Spike (S)-Protein-Based Commercial Immunoassay for the Detection of Anti-SARS-CoV-2 IgG

open access: yesMicroorganisms, 2021
Background: The investigation of the antibody response to SARS-CoV-2 represents a key aspect in facing the COVID-19 pandemic. In the present study, we compared the new Immundiagnostik IDK® anti-SARS-CoV-2 S1 IgG assay with four widely-used commercial ...
Kirsten Alexandra Eberhardt   +16 more
doaj   +1 more source

Estimating the Neutralizing Effect and Titer Correlation of Semi-Quantitative Anti-SARS-CoV-2 Antibody Immunoassays

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
For the clinical application of semi-quantitative anti-SARS-CoV-2 antibody tests, the analytical performance and titer correlation of the plaque reduction neutralization test (PRNT) need to be investigated.
Beomki Lee   +17 more
semanticscholar   +1 more source

Moving beyond Titers

open access: yesVaccines, 2022
Vaccination to prevent and even eliminate disease is amongst the greatest achievements of modern medicine. Opportunities remain in vaccine development to improve protection across the whole population. A next step in vaccine development is the detailed molecular characterization of individual humoral immune responses against a pathogen, especially the ...
Benjamin D. Brooks   +4 more
openaire   +3 more sources

Randomized Controlled Trial of Early Outpatient COVID-19 Treatment with High-Titer Convalescent Plasma

open access: yesmedRxiv, 2021
BACKGROUND: The efficacy of polyclonal high titer convalescent plasma to prevent serious complications of COVID-19 in outpatients with recent onset of illness is uncertain.
D. Sullivan   +57 more
semanticscholar   +1 more source

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