Improved Titer in Late-Stage Mammalian Cell Culture Manufacturing by Re-Cloning
Improving productivity to reduce the cost of biologics manufacturing and ensure that therapeutics can reach more patients remains a major challenge faced by the biopharmaceutical industry.
Qin He +15 more
doaj +1 more source
Low–Temperature Storage and the Viability Preservation of Streptomyces [PDF]
The most effective way to store microorganisms of different taxonomic groups is at low temperatures from minus 12°C to minus 150°C. The present research features the influence of low temperature (minus 12°C and 18°C) on the viability of collection ...
Vybornova T., Sharova N., Printseva A.
doaj +1 more source
Has Convalescent Plasma Therapy Hesitancy Increased COVID-19 Mortality?
We bring to you our viewpoint and a snapshot of the journey of convalescent plasma therapy (CPT) in the management of ongoing coronavirus disease 2019 (COVID-19) pandemic.
Purvish M. Parikh +3 more
doaj +1 more source
Serological Screening for Antibodies against SARS-CoV-2 in Dutch Shelter Cats
The COVID-19 pandemic raised concerns that companion animals might be infected with, and could become a reservoir of, SARS-CoV-2. As cats are popular pets and susceptible to Coronavirus, we investigated the seroprevalence of SARS-CoV-2 antibodies in ...
W. J. R. van der Leij +5 more
doaj +1 more source
A Novel Unsupervised Method to Identify Genes Important in the Anti-viral Response: Application to Interferon/Ribavirin in Hepatitis C Patients [PDF]
Background: Treating hepatitis C with interferon/ribavirin results in a varied response in terms of decrease in viral titer and ultimate outcome. Marked responders have a sharp decline in viral titer within a few days of treatment initiation, whereas in ...
A Hartnell +45 more
core +4 more sources
Reproducibility of serological titers [PDF]
Serologists are making increasing use of the term "reproducibility" when referring to the reliability or repeatability of serological tests. The practical use of the concept, however, has been limited by the absence of an appropriate numerical scale on which differing reproducibilities can be quantified and objectively compared.
R J, Wood, T M, Durham
openaire +2 more sources
GADA titer-related risk for organ-specific autoimmunity in LADA subjects subdivided according to gender (NIRAD study 6). [PDF]
CONTEXT: Latent autoimmune diabetes in adults (LADA) includes a heterogeneous population wherein, based on glutamic acid decarboxylase antibody (GADA) titer, different subgroups of subjects can be identified.
Bosi, E +11 more
core +1 more source
Economic analysis of royalactin production under uncertainty: Evaluating the effect of parameter optimization. [PDF]
Royalactin is a protein with several different potential uses in humans. Research, in insects and in mammalian cells, has shown that it can accelerate cell division and prevent apoptosis.
Aguilar-Yañez, JM +3 more
core +1 more source
Variation in dengue virus plaque reduction neutralization testing: systematic review and pooled analysis. [PDF]
BackgroundThe plaque reduction neutralization test (PRNT) remains the gold standard for the detection of serologic immune responses to dengue virus (DENV).
Cummings, Derek AT +3 more
core +3 more sources
. The special study to find a more cost-effective source of immunodiagnostic products was conducted. Determination of titers of specific immunoglobulins to HBsAg in serum and egg yolk of quail using different preparation for immunization showed that the ...
V. B. Sboychakov +2 more
doaj +1 more source

