Integration of Bayesian optimization and solution thermodynamics to optimize media design for mammalian biomanufacturing. [PDF]
Ndahiro N+5 more
europepmc +1 more source
Optimum Conditions for the Assay of Hemolytic Complement Titer of Carp and Seasonal Variation of the Titers [PDF]
Tomoki Yano, Miki Nakao, Hiroko Ando
openaire +2 more sources
Kindlin Regulates Mechanosensitive Activation and Adhesion Assembly of Integrin beta6
Extracellular matrix compliance plays a critical role in the regulation of integrin‐mediated adhesion and cell motility. Here, it is reported that strengthening the kindlin2‐integrin β6 interaction overcomes the dependence on extracellular substrate stiffness and promotes integrin β6‐mediated cell migration.
Wan Ning Lee+3 more
wiley +1 more source
A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage [PDF]
Diamond, Michael S+3 more
core +2 more sources
IL-2 and IL-15 augment HBV therapeutic vaccination and PD1 blockade for functional cure in the AAV-HBV mouse model. [PDF]
Lewis G+7 more
europepmc +1 more source
Osteoblast‐CD4+ CTL Crosstalk Mediated by SIRT1/DAAM2 Axis Prevents Age‐Related Bone Loss
In the osteoblastic niche, SIRT1 activates and recruits CD4+ CTLs by increasing DAAM2 expression via EZH2 deacetylation and boosting the secretion of key chemokines, such as CCL3, CCL5, and CXCL10. Then, CD4+ CTL directly eliminates senescent osteoblasts in an MHC‐II‐dependent way, thereby slowing down the process of bone ageing and effectively ...
Bin Yang+20 more
wiley +1 more source
Analysis of Treatment and Subsequent Pregnancy Outcomes in Patients With Antinuclear Antibody-Positive Recurrent Spontaneous Abortion. [PDF]
Wang A+5 more
europepmc +1 more source
m6A modification stabilizes Slc15a3 mRNA in macrophages, activating the SLC15A3‐TASL‐IRF5 axis and promoting psoriatic inflammation. Abstract Impaired N6‐methyladenosine (m6A) modification has been implicated in regulating various inflammatory diseases, but its role in psoriasis remains unclear.
Tao Huang+13 more
wiley +1 more source
Liver transplantation in positive cytotoxic crossmatch cases using FK506, high-dose steroids, and prostaglandin E [PDF]
Iwaki, Y, Starzl, TE, Takaya, S
core +1 more source
A Prospective Study of Immune Response After COVID-19 or Vaccination and Correlation Between Avidity Index and Neutralizing Capacity. [PDF]
Löfström E+7 more
europepmc +1 more source