Results 11 to 20 of about 638,613 (387)

Titer regulation in arthropod-Wolbachia symbioses [PDF]

FEMS Microbiology Letters, 2019
ABSTRACT Symbiosis between intracellular bacteria (endosymbionts) and animals are widespread. The alphaproteobacterium Wolbachia pipientis is known to maintain a variety of symbiotic associations, ranging from mutualism to parasitism, with a wide range of invertebrates.
Sergio López-Madrigal, Elves H Duarte
openaire   +4 more sources

Coccidioidomycosis Complement Fixation Titer Trends in the Age of Antifungals. [PDF]

Journal of Clinical Microbiology, 2018
Coccidioidomycosis is associated with a broad spectrum of illness severity, ranging from asymptomatic or self-limited pulmonary infection to life-threatening manifestations of disseminated disease.
Bays, Derek, Dinh, Bao-Tran N, McHardy, Ian H, Pappagianis, Demosthenes, Stewart, Ethan, Thompson, George R, Waldman, Sarah   +6 more
core   +2 more sources

Early High-Titer Plasma Therapy to Prevent Severe Covid-19 in Older Adults

New England Journal of Medicine, 2021
Background Therapies to interrupt the progression of early coronavirus disease 2019 (Covid-19) remain elusive. Among them, convalescent plasma administered to hospitalized patients has been unsuccessful, perhaps because antibodies should be administered ...
R. Libster, Gonzalo Pérez Marc, Diego Wappner, Silvina Coviello, Alejandra M Bianchi, Virginia Braem, I. Esteban, M. Caballero, Cristian Wood, M. Berrueta, Aníbal Rondan, G. Lescano, P. Cruz, Yvonne Ritou, Valeria Fernández Viña, D. Álvarez Paggi, S. Esperante, Adrián Ferreti, G. Ofman, Álvaro Ciganda, Rocio Rodriguez, J. Lantos, R. Valentini, Nicolás Itcovici, A. Hintze, M. Oyarvide, Candela Etchegaray, Alejandra Neira, Ivonne Name, Julieta Alfonso, Rocío López Castelo, G. Caruso, Sofía Rapelius, F. Álvez, F. Etchenique, Federico Dimase, D. Álvarez, S. Aranda, Clara Sánchez Yanotti, Julián De Luca, Sofía Jares Baglivo, S. Laudanno, Florencia Nowogrodzki, R. Larrea, M. Silveyra, Gabriel Leberzstein, Alejandra Debonis, J. Molinos, M. González, E. Perez, Nicolás Kreplak, Susana Pastor Argüello, L. Gibbons, F. Althabe, E. Bergel, F. Polack   +55 more
semanticscholar   +1 more source

Neutralization titer biomarker for antibody-mediated prevention of HIV-1 acquisition

Nature Medicine, 2022
The Antibody Mediated Prevention trials showed that the broadly neutralizing antibody (bnAb) VRC01 prevented acquisition of human immunodeficiency virus-1 (HIV-1) sensitive to VRC01.
P. Gilbert, Yunda Huang, Allan C. deCamp, S. Karuna, Yuanyuan Zhang, Craig A. Magaret, E. Giorgi, B. Korber, P. Edlefsen, R. Rossenkhan, M. Juraska, Erika Rudnicki, Nidhi Kochar, Ying Huang, Lindsay N. Carpp, D. Barouch, N. Mkhize, T. Hermanus, Prudence Kgagudi, V. Bekker, H. Kaldine, Rutendo E Mapengo, Amanda Eaton, Elize Domin, Carl J. West, Wenhong Feng, Haili Tang, K. Seaton, Jack R. Heptinstall, Caroline Brackett, Kelvin Chiong, G. Tomaras, P. Andrew, B. Mayer, D. Reeves, M. Sobieszczyk, N. Garrett, Jorge Sanchez, C. Gay, J. Makhema, C. Williamson, J. Mullins, J. Hural, M. Cohen, L. Corey, D. Montefiori, L. Morris   +46 more
semanticscholar   +1 more source

Estimating the Neutralizing Effect and Titer Correlation of Semi-Quantitative Anti-SARS-CoV-2 Antibody Immunoassays

Frontiers in Cellular and Infection Microbiology, 2022
For the clinical application of semi-quantitative anti-SARS-CoV-2 antibody tests, the analytical performance and titer correlation of the plaque reduction neutralization test (PRNT) need to be investigated.
Beomki Lee, J. Ko, Jiho Park, H. Moon, J. Baek, Sunhee Jung, Hee‐Young Lim, Kyung-Chang Kim, K. Huh, S. Cho, C. Kang, D. Chung, H. Huh, C. Chung, Yae-Jean Kim, E. Joo, E. Kang, K. Peck   +17 more
semanticscholar   +1 more source

Genome-scale target identification in Escherichia coli for high-titer production of free fatty acids

Nature Communications, 2021
To construct a superior microbial cell factory for chemical synthesis, a major challenge is to fully exploit cellular potential by identifying and engineering beneficial gene targets in sophisticated metabolic networks.
Lixia Fang, Jie Fan, Shulei Luo, Yaru Chen, Congya Wang, Yingxiu Cao, Hao Song   +6 more
semanticscholar   +1 more source

Significantly Decreased Mortality in a Large Cohort of Coronavirus Disease 2019 (COVID-19) Patients Transfused Early with Convalescent Plasma Containing High-Titer Anti–Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Protein IgG

American Journal of Pathology, 2020
Coronavirus disease 2019 (COVID-19) convalescent plasma has emerged as a promising therapy and has been granted Emergency Use Authorization by the US Food and Drug Administration for hospitalized COVID-19 patients.
E. Salazar, P. Christensen, E. Graviss, D. Nguyen, Brian Castillo, Jian Chen, B. Lopez, T. Eagar, X. Yi, P. Zhao, J. Rogers, Ahmed Shehabeldin, D. Joseph, F. Masud, C. Leveque, R. Olsen, D. Bernard, J. Gollihar, J. Musser   +18 more
semanticscholar   +1 more source

The association between obesity and peak antibody titer response in COVID‐19 infection

Obesity, 2021
Obesity is associated with severe coronavirus disease 2019 (COVID‐19) infection. Disease severity is associated with a higher COVID‐19 antibody titer.
S. Soffer, Benjamin S. Glicksberg, E. Zimlichman, Orly Efros, M. Levin, R. Freeman, D. Reich, Eyal Klang   +7 more
semanticscholar   +1 more source

High neutralizing antibody titer in intensive care unit patients with COVID-19

Emerging Microbes and Infections, 2020
Coronavirus disease 2019 (COVID-19) has a wide spectrum of disease severity from mild upper respiratory symptoms to respiratory failure. The role of neutralizing antibody (NAb) response in disease progression remains elusive.
Li Liu, K. To, Kwok-Hung Chan, Y. Wong, R. Zhou, Ka-Yi Kwan, C. Fong, Lin-Lei Chen, Charlotte Yee-Ki Choi, Lu Lu, O. Tsang, W. Leung, W. To, I. Hung, K. Yuen, Zhiwei Chen   +15 more
semanticscholar   +1 more source

Improved Titer in Late-Stage Mammalian Cell Culture Manufacturing by Re-Cloning

Bioengineering, 2022
Improving productivity to reduce the cost of biologics manufacturing and ensure that therapeutics can reach more patients remains a major challenge faced by the biopharmaceutical industry.
Qin He, Matthew S. Rehmann, Jun Tian, Jianlin Xu, Luzmary Sabino, Erik Vandermark, Ziev Basson, Iris Po, Kathleen Bierilo, Gabi Tremml, Giovanni Rizzi, Erik F. Langsdorf, Nan-Xin Qian, Michael C. Borys, Anurag Khetan, Zheng-Jian Li   +15 more
doaj   +1 more source