Results 221 to 230 of about 413,621 (336)

Preparation and Storage of High-Titer Lactic Streptococcus Bacteriophages1 [PDF]

open access: gold, 1974
J. Nyiendo   +3 more
openalex   +1 more source

High‐Throughput MicroED for Probing Ion Channel Dynamics

open access: yesAdvanced Science, EarlyView.
High‐throughput MicroED offers a new approach for visualizing ion channel dynamics. This approach reveals NaK’s sodium binding modes and NaK2CNG’s potassium‐induced selectivity filter dilation and gating. By capturing these distinct structures, this work challenges traditional models of ion channel permeation and selectivity. Abstract Ion channels play
Marc J Gallenito   +4 more
wiley   +1 more source

The Neglected Role of GSDMD C‐Terminal in Counteracting Type I Interferon Signaling

open access: yesAdvanced Science, EarlyView.
The C‐terminal domain of Gasdermin D (GSDMD‐CT) shows functions beyond pyroptosis. GSDMD‐CT negatively regulates IFN‐I signaling during viral infection by triggering autophagic degradation of RIG‐I and TBK1. GSDMD‐CT interacts with retinoic acid‐inducible gene‐I (RIG‐I) and tank‐binding kinase 1 (TBK1), leading to TRIM28‐mediated ubiquitination and ...
Weilv Xu   +17 more
wiley   +1 more source

Bayesian optimization and machine learning for vaccine formulation development. [PDF]

open access: yesPLoS One
Li L   +5 more
europepmc   +1 more source

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