Results 291 to 300 of about 638,613 (387)

NS3-K40R increases viral titers in Stat1^−/− mice but has no effect in immunocompetent mice.

Valerie J. Rodriguez-Irizarry (13204671), Robert W. Maples (13222462), Julie K. Pfeiffer (21594705)   +2 more
openalex   +1 more source

Distortion and Tits alternative in smooth mapping class groups

, 2015
Hurtado, Sebastian, Emmanuel Militon
openalex   +1 more source

Influence of using sage powder (Salvia officinalis) on performance, blood cells, immunity titers, biochemical parameters and small intestine morphology in broiler chickens. [PDF]

, 2020
Mostafa Farhadi, M. Hedayati, M. Manafi, Saeed Khalaji   +3 more
openalex  

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

Advanced Science, EarlyView.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin, Wenzhuo Xu, Kang Liu, Ping Wang, Zhenzhen Zhu, Wenyu Lu, Zhe Zheng, Xiaoqian Peng, Xunkai Yin, Shulan Mei, An Pan, Jian Liu, Lihong Hu   +12 more
wiley   +1 more source

COVID-19-Associated Acquired Hemophilia A With an Exceptionally High Inhibitor Titer: A Case of Remission and Overwhelming Sepsis. [PDF]

Cureus
Pathak S.
europepmc   +1 more source

MVP Inhibits Influenza A Virus‐Induced Ferroptosis by Targeting IRF1 and Increasing FSP1 Activity

Advanced Science, EarlyView.
During IAV infection, MVP inhibits IRF1 polyubiquitination, thereby relieving IRF1‐mediated transcriptional inhibition of FSP1. Consequently, this leads to an upregulation of FSP1 expression, thereby reinforcing the inhibition of ferroptosis. In addition, the MVP can promote myristoylation and ubiquitination of FSP1, enabling its membrane localization ...
Yingbo Chen, Paili Lin, Yongfang Xia, Zhiqiang Liu, Zilu Cheng, Qingmei Zhu, Shiqi Wan, Xiaoyu Chen, Haiyan Bao, Renbo Qiao, Gechang Zhong, Ying Zhu, Shi Liu   +12 more
wiley   +1 more source

Late post-transplant recurrence of an anti-myeloperoxydase antibody-associated vasculitis in a former double-positive patient: a case report. [PDF]

Front Immunol
Chenaf-Benabdelmoumene N, Chabannes M, Ducloux D, Bamoulid J, Crepin T, Lang S.   +5 more
europepmc   +1 more source

Systematically Engineering for Efficient Production of 3‐Methyl‐1‐Butanol in Escherichia coli

Advanced Science, EarlyView.
An integrated metabolic engineering strategy was established for high‐level 3‐methyl‐1‐butanol biosynthesis in Escherichia coli. Molecular dynamics‐guided semi‐rational engineering of dihydroxyacid dehydratase uncovered and relieved key catalytic bottlenecks, while adaptive laboratory evolution enhanced strain robustness.
Nanfei Geng, Hao Liu, Haolin Han, Meng Meng, Shaojie Wang, Tianwei Tan, Haijia Su   +6 more
wiley   +1 more source

Clinical manifestations and serological rebound in HIV and syphilis co-infection: a case report and literature review. [PDF]

AIDS Res Ther
Zhang M, Meng J, Luo H, Huang J, Yang R.
europepmc   +1 more source

Decline in the frequency and benefits of multiple brooding in great tits as a consequence of a changing environment

, 2009
Arild Husby, Loeske E. B. Kruuk, Marcel E. Visser   +2 more
openalex   +2 more sources