Results 121 to 130 of about 256,556 (266)

Implementation and Validation of Titratable Cysteine in GROMACS-Based Constant-pH Molecular Dynamics. [PDF]

J Chem Theory Comput
Capelli R.
europepmc   +1 more source

Thermally Processable, Transparent, Mechanically Tunable and Robust Bioplastics From Wastepaper

Advanced Science, EarlyView.
Unlike conventional inefficient or low‐value wastepaper recycling, a directional transformation strategy is employed to convert whole wastepaper into intact bioplastics with tunable mechanical properties in our work. These bioplastics can be processed into flexible bags or rigid containers and exhibit high transparency, water resistance, repairability,
Zhezhe Zhou, Tao Chu, Boyou Hou, Mark Lynch, Siqi Huo, Min Hong, Jianguo Yang, Paulomi (Polly) Burey, Qiang Gao, Guobo Huang, Pingan Song   +10 more
wiley   +1 more source

ElecTrical Impedance TomogRaphy vs dynamic compliANce guided positive end-expiratory pressure Titration during laparoscopic gynaecological surgery (TITRANT): protocol for a multicentre randomised trial. [PDF]

BMJ Open
Geréd C, Szigetváry C, Mikó A, Bokrétás GP, Lovas A, Forgács R, Nemes M, Molnár Z, Ruszkai Z.   +8 more
europepmc   +1 more source

RNF138‐Mediated Ubiquitination and Degradation of NS5 Restricts Tick‐Borne Encephalitis Virus Infection

Advanced Science, EarlyView.
Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun, Weijing Yang, Hao Zhou, Shuai Li, Xin Jiang, Jianyang Gu, Wenyan Zhang   +6 more
wiley   +1 more source

InNMR: Direct <i>In Situ</i> Studies of Transport Phenomena Enabled by an Innovative NMR-Tube Insert. [PDF]

Anal Chem
Frison A, Sørensen MM, Prince K, Mayzel M, Aachmann FL, Flaten GE, Rainsford P, Isaksson J.   +7 more
europepmc   +1 more source

Allosteric Inhibition of Polycomb Repressive Complex 2 by an EZH2‐Selective Small Molecule Inhibitor

Advanced Science, EarlyView.
The study characterizes C36, a highly selective EZH2/PRC2 inhibitor that acts via a novel allosteric mechanism. Unlike previous inhibitors, C36 inhibits EZH2/PRC2 by disrupting the allosteric communication between EZH2 and EED in a SAM‐noncompetitive manner.
Ting Cao, Dongdong Liu, Haishan Gao, Chenyang Qin, Wen Zhang, Ziyun Lu, Dongxia Tan, Yuxiu Qu, Yusong Liu, Zhiran Zou, Hongtao Yu, Wei Qi   +11 more
wiley   +1 more source

Manic episode following lurasidone initiation in bipolar I disorder: a case report. [PDF]

Front Psychiatry
Alzain NM, Al-Awad FA, Alzahrani SA, Almsned FM.   +3 more
europepmc   +1 more source

p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

Advanced Science, EarlyView.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu, Zhihao Zhan, Xiaoxiang Pan, Xinyue Zhang, Penggang Liu, Jing Sun, Xiulong Xu   +6 more
wiley   +1 more source

Does Dynamic Compliance-Guided PEEP Titration Reduce Postoperative Pulmonary Aeration Loss in Laparoscopic Bariatric Surgery? Randomized Controlled Trial. [PDF]

J Clin Med
Göçmen D, Masatlıoğlu Y, Özaltun F, Günal Ö, Umuroğlu T.   +4 more
europepmc   +1 more source

TiTrATE [PDF]

Neurologic Clinics, 2015
David E. Newman-Toker, Jonathan A. Edlow
openaire   +1 more source