Results 41 to 50 of about 256,556 (266)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Rapid Field Assay for Pineapple Fruit Acidity

open access: yesHortTechnology, 2020
The sugar-to-acid ratio of pineapple (Ananas comosus L.) contributes toward giving the fruit its unique flavor. This ratio is an important indicator of both commercial and organoleptic ripeness, and it is useful in determining a harvest date. Citric acid
Robert E. Paull   +2 more
doaj   +1 more source

Determination of alkalinity in the water sample: a theoretical approach

open access: yesChemistry Teacher International, 2023
Determination of alkalinity of water sample is generally carried out experimentally by titration method using a proper indicator. In the literature, five different cases of possible alkalinities are reported based on the experimental data of acid ...
Dhoke Shailesh K.
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Functional Groups and Structural Characterization of Unmodified and Functionalized Lignin by Titration, Elemental Analysis, 1H NMR and FTIR Techniques [PDF]

open access: yesعلوم و تکنولوژی پلیمر, 2017
Lignin is the second most abundant polymer in the world after cellulose. Therefore, characterization of the structure and functional groups of lignin in order to assess its potential applications in various technical fields has become a necessity. One of
Ramin Bairami Habashi, Mahdi Abdollahi
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

An Open-Label, Randomized, Prospective, Comparative, Three-Arm Clinical Trial to Evaluate the Safety and Effectiveness of Apremilast with Three Different Titration Methods in Patients with Chronic Plaque Psoriasis in India

open access: yesPsoriasis: Targets and Therapy, 2022
Vishalakshi Viswanath,1 Pradnya Joshi,1 Prakash Lawate,1 Dakshata Tare,1 Dhiraj Dhoot,2 Namrata Mahadkar,2 Hanmant Barkate2 1Department of Dermatology, Rajiv Gandhi Medical College, Thane, Mumbai, India; 2Department of Global Medical Affairs, Glenmark ...
Viswanath V   +6 more
doaj  

The titrating conditions in the potentiometric titration of zinc

open access: yesBUNSEKI KAGAKU, 1964
硫酸酸性におけるフェロシアン化カリウムによる亜鉛の定量を,さまざまな滴定条件のもとに,白金-タングステン双金属電極を用いて電位差滴定を行ない,滴定に及ぼす諸影響を検討した.20℃では硫酸濃度,硫酸アンモニウム濃度によって終点の滴定量が異なるが,滴定溶液の容積100mlあたり硫酸濃度範囲0~0.05N,硫酸アンモニウム20gで一定の滴定速度のもとに行なうと,終点までの滴定量の再現性および電位差滴定曲線がともに良好で,終点における電位差変化が大きい.亜鉛濃度0.0025~0.0125Mの溶液を,滴定誤差約+1.5%で定量することができる.60℃ではすみやかに終点に達し,硫酸濃度,硫酸アンモニウム濃度,滴定時間の影響はより小さくなるが,終点における電位差変化が小さい.滴定誤差は約-1.2%である.
MIYAZAWA, Saburo, OTSUKA, Fumihiko
openaire   +2 more sources

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong   +10 more
wiley   +1 more source

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